
ICU Ed and Todd-Cast
Two critical care guys walk into a recording studio and breakdown intensive care trials both old and new! We'll also do deep dives on specific topics important to practicing intensive care medicine and have special guests talking about their area of expertise! This podcast is made for educational purposes. The content provided in this podcast, and in any linked materials, is not intended and should not be construed as medical advice and should not be used to diagnose or treat any medical condition. We try to stay away from opinions but all opinions represent our own and not of any entity we work for. Please keep this in mind as you enjoy the podcast!
Latest episodes

Aug 29, 2023 • 26min
New: Methylene Blue in Septic Shock
Send us a Text Message (please include your email so we can respond!)Episode 18! In this episode we talk about "Early adjunctive methylene blue in patients with septic shock: a randomized controlled trial" published March 2023 by Ibarra-Estrada et al in Critical Care. We made a planning mistake so no old article today so we left it short!Methylene blue: https://pubmed.ncbi.nlm.nih.gov/36915146/If you enjoy the show be sure to like and subscribe, leave that 5 star review! Be sure to follow us on the social @icucast for the associated figures, comments, and other content not available in the audio format! Email us at icuedandtoddcast@gmail.com with any questions or suggestions! Thank you Mike Gannon for the intro and exit music!

Aug 15, 2023 • 40min
New/Old: WATERFALL and EGDT
Send us a Text Message (please include your email so we can respond!)Episode 17! In this episode we talk about "Aggressive of Moderate Fluid Resuscitation in Acute Pancreatitis" published September 2022 by de-Madaria et al in the New England Journal of Medicine and then talk about the landmark study "Early Goal-Directed Therapy in the Treatment of Severe Sepsis and Septic Shock" by Rivers et al also NEJM but November 2001WATERFALL: https://pubmed.ncbi.nlm.nih.gov/36103415/EGDT: https://pubmed.ncbi.nlm.nih.gov/11794169/If you enjoy the show be sure to like and subscribe, leave that 5 star review! Be sure to follow us on the social @icucast for the associated figures, comments, and other content not available in the audio format! Email us at icuedandtoddcast@gmail.com with any questions or suggestions! Thank you Mike Gannon for the intro and exit music!

Aug 1, 2023 • 48min
New/Old: Phenobarbital for alcohol withdrawal and TRICC
Send us a Text Message (please include your email so we can respond!)Episode 16! In this episode we talk about "Phenobarbital-Based Protocol for Alcohol Withdrawal Syndrome in a Medical ICU: Pre-Post Implementation Study" published April 2023 by Alwakeel et al and then talk about the landmark study TRICC or "A multicenter, randomized, controlled clinical trial of transfusion requirements in critical care"We also explore car donation jingles (1-877 KARS 4 KIDSPhenobarbital: https://pubmed.ncbi.nlm.nih.gov/37091477/TRICC: https://pubmed.ncbi.nlm.nih.gov/9971864/TRISS: https://pubmed.ncbi.nlm.nih.gov/23281973/Transfusion in Upper GI bleeds: https://pubmed.ncbi.nlm.nih.gov/25270275/If you enjoy the show be sure to like and subscribe, leave that 5 star review! Be sure to follow us on the social @icucast for the associated figures, comments, and other content not available in the audio format! Email us at icuedandtoddcast@gmail.com with any questions or suggestions! Thank you Mike Gannon for the intro and exit music!

Jul 18, 2023 • 40min
New/Obs: BOX-BP and WEAN-SAFE
Send us a Text Message (please include your email so we can respond!)Episode 15! In this episode we talk about "Blood-Pressure Targets in Comatose Survivors of Cardiac Arrest" published October 2022 by Kjaergaard (apologies in advance for the pronounciation...) et al and then talk about the prospective observational cohort "Weaning from mechanical ventilation in intensive care units across 50 countries (WEAN SAFE)"BOX-BP: https://pubmed.ncbi.nlm.nih.gov/36027564/WEAN SAFE: https://pubmed.ncbi.nlm.nih.gov/36693401/CT scan after cardiac arrest: https://pubmed.ncbi.nlm.nih.gov/37019352/If you enjoy the show be sure to like and subscribe, leave that 5 star review! Be sure to follow us on the social @icucast for the associated figures, comments, and other content not available in the audio format! Email us at icuedandtoddcast@gmail.com with any questions or suggestions! Thank you Mike Gannon for the intro and exit music!

Jul 4, 2023 • 41min
New/Old: ARDS Guidelines and ARMA
Send us a Text Message (please include your email so we can respond!)Summer is here and we're getting a chance to catch our breath! Unless there is a surprise article drop we anticipate that our next few episodes are going to be a little bit different as we catch up on non-RCT happenings in the critical care world. This episode is the same, our discussion on ARDS is a fascinating history lesson blended in with current insights.ARDS Guidelines: https://pubmed.ncbi.nlm.nih.gov/37326646/ARMA: https://pubmed.ncbi.nlm.nih.gov/10793162/If you enjoy the show be sure to like and subscribe, leave that 5 star review! Be sure to follow us on the social @icucast for the associated figures, comments, and other content not available in the audio format! Email us at icuedandtoddcast@gmail.com with any questions or suggestions! Thank you Mike Gannon for the intro and exit music!

Jun 20, 2023 • 42min
CCR23 Recap and EXIT-SEP
Send us a Text Message (please include your email so we can respond!)Episode 13! We made it this far! Instead of keying in on one major article from the Critical Care Reviews Conference 2023 we decided to do a pot pourri of the entire conference. It was quite the whirlwind, if there is any point or trial you want us to elaborate please contact us and let us know!Otherwise we discuss EXIT-SEP in our "short" discussion section. This was published in JAMA Internal Medicine by Liu et al evaluating XueBiJing Injection versus placebo in patients with sepsis. EXIT-SEP: https://pubmed.ncbi.nlm.nih.gov/37126332/As always, if you appreciate the content please share with friends or social media!If you enjoy the show be sure to like and subscribe, leave that 5 star review! Be sure to follow us on the social @icucast for the associated figures, comments, and other content not available in the audio format! Email us at icuedandtoddcast@gmail.com with any questions or suggestions! Thank you Mike Gannon for the intro and exit music!

Jun 16, 2023 • 54min
New: DEVICE with Matt Prekker
Send us a Text Message (please include your email so we can respond!)This is a little off schedule (and a little long!) but we were SO EXCITED to have the opportunity to sit down and talk with Matt Prekker, the lead author on the DEVICE trial evaluating video versus direct laryngoscopy for tracheal intubation which was published TODAY, June 2023, in the New England Journal of Medicine and presented TODAY at CCR Meeting 2023. DEVICE: https://www.nejm.org/doi/full/10.1056/NEJMoa2301601?query=featured_home(DOI: 10.1056/NEJMoa2301601)INTUBE: https://pubmed.ncbi.nlm.nih.gov/33755076/Please excuse any audio issues! First time recording remotely and we will address volume issues for next time.If you enjoy the show be sure to like and subscribe, leave that 5 star review! Be sure to follow us on the social @icucast for the associated figures, comments, and other content not available in the audio format! Email us at icuedandtoddcast@gmail.com with any questions or suggestions! Thank you Mike Gannon for the intro and exit music!

Jun 6, 2023 • 35min
New: PACER
Send us a Text Message (please include your email so we can respond!)Episode 11/12 (depending on how you count the ATS episode)! This time we discuss "Platelet Transfusion before CVC Placement in Patients with Thrombocytopenia" published in NEJM May 2023. Apologies for the lack of old articles, with summer travel plans we've prepped for a couple but ran out of recording time. When things slow down a bit, we'll get back into our normal flow.PACER: https://pubmed.ncbi.nlm.nih.gov/37224197/If you enjoy the podcast please share on social media or by word of mouth! Thank you!If you enjoy the show be sure to like and subscribe, leave that 5 star review! Be sure to follow us on the social @icucast for the associated figures, comments, and other content not available in the audio format! Email us at icuedandtoddcast@gmail.com with any questions or suggestions! Thank you Mike Gannon for the intro and exit music!

May 23, 2023 • 32min
ATS 2023: Goals of Care Discussions in Hospitalized Patients
Send us a Text Message (please include your email so we can respond!)ATS 2023! Unfortunately for us, there were more breaking pulmonary articles compared to critical care but we did get this great article by the late Dr. Curtis published in JAMA during the conference "Intervention to Promote Communication About Goals of Care for Hospitalized Patients With Serious Illness". Article: https://pubmed.ncbi.nlm.nih.gov/37210665/If you enjoy the podcast please share on social media or by word of mouth! Thank you!If you enjoy the show be sure to like and subscribe, leave that 5 star review! Be sure to follow us on the social @icucast for the associated figures, comments, and other content not available in the audio format! Email us at icuedandtoddcast@gmail.com with any questions or suggestions! Thank you Mike Gannon for the intro and exit music!

May 9, 2023 • 42min
New: AID-ICU
Send us a Text Message (please include your email so we can respond!)Episode 10! In this episode we rambled a little bit and limited ourselves to just our new article which was "Haloperidol for the Treatment of Delirium in ICU Patients" published by Andersen-Ranberg et al in NEJM 2022. Of note, we go back and forth a little bit between "haloperidol" and the brand name "Haldol" but we hope it is similar enough it doesn't impede your listening!AID-ICU: https://pubmed.ncbi.nlm.nih.gov/36286254/AID-ICU Bayesian: https://pubmed.ncbi.nlm.nih.gov/36971791/MIND-USA: https://pubmed.ncbi.nlm.nih.gov/30346242/If you enjoy the podcast please share on social media or by word of mouth! Thank you!If you enjoy the show be sure to like and subscribe, leave that 5 star review! Be sure to follow us on the social @icucast for the associated figures, comments, and other content not available in the audio format! Email us at icuedandtoddcast@gmail.com with any questions or suggestions! Thank you Mike Gannon for the intro and exit music!