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ICU Ed and Todd-Cast
Old/Old/Old: VASST, VANISH, ATHOS-3
Feb 27, 2024
In this episode, the hosts dive into the world of vasopressors, focusing on vasopressin and angiotensin-2 in trials like VASST, VANISH, and ATHOS-3. They discuss the challenges of managing blood pressure, trial outcomes, and implications for clinical practice. The chapter also explores ethical debates, treatment strategies, and the efficacy of different pressors in critical care settings.
01:03:23
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Quick takeaways
- Vasopressin is commonly used as a second-pressor in sepsis management compared to angiotensin-2 due to accessibility.
- Conducting a factorial study like the Vanish trial involves evaluating two interventions simultaneously with consistent criteria.
Deep dives
Vasopressin Use in Sepsis Management
Vasopressin and angiotensin2 are discussed in relation to vasopressor use in sepsis management. The podcast delves into how these non-norepinephrine pressors are utilized, highlighting vasopressin as a common second-pressor in sepsis cases compared to angiotensin2, which may be less accessible in many institutions. The episode emphasizes listener feedback on blood pressure management, particularly focusing on the role of vasopressin in clinical practice.
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Discover
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