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Old/Old/Old: VASST, VANISH, ATHOS-3

ICU Ed and Todd-Cast

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Exploring the Use of Vasopressin in Clinical Practice

The chapter delves into the trials comparing norepinephrine and vasopressin in septic shock patients, analyzing mortality rates and business implications. Speakers discuss their protocol adjustments based on cost and guidelines, focusing on when to stop vasopressin and titrate norepinephrine. The conversation also covers the method of spiking a new vasopressin bag, the concept of vanish, and the design challenges of a two by two factorial study.

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