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Old/Old/Old: VASST, VANISH, ATHOS-3

ICU Ed and Todd-Cast

CHAPTER

Challenges and Outcomes of a Clinical Trial Investigating Vasopressin and Norepinephrine

The chapter explores the difficulties in patient enrollment for a trial due to strict criteria, analyzing the impacts of excluding certain patients and the complexities of trial design. It discusses the trial outcomes, noting no significant difference between various treatment groups and raising concerns about the use of vasopressin as the first choice pressor. The conversation also touches on alternative pressor options and the importance of data-driven decision-making in medical practices.

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