ICU Ed and Todd-Cast

Send us a Text Message (please include your email so we can respond!)We start our Critical Care Reviews Down Under coverage with RSI talking with the first author of the "Ketamine versus Etomidate for Adults Receiving Emergency Endotrachael Intubation", Jonathan Casey! We will pick up the rest of our CCR Down Under Coverage after the holiday break!If you enjoy the show be sure to like and subscribe, leave that 5 star review! Be sure to follow us on the social @icucast for the associated figures, comments, and other content not available in the audio format! Email us at icuedandtoddcast@gmail.com with any questions or suggestions! Thank you Mike Gannon for the intro and exit music!

Send us a Text Message (please include your email so we can respond!)Episode 79! We talk all about perfusion with arterial lines in EVERDAC and personalized resuscitation with ANDROMEDA SHOCK 2! EVERDAC: https://pubmed.ncbi.nlm.nih.gov/41159885/EVERDAC (NEJM): https://www.nejm.org/doi/10.1056/NEJMoa2502136ANDROMEDA SHOCK 2: https://pubmed.ncbi.nlm.nih.gov/41159835/ANDROMEDA SHOCK 2(JAMA): https://jamanetwork.com/journals/jama/fullarticle/2840823If you enjoy the show be sure to like and subscribe, leave that 5 star review! Be sure to follow us on the social @icucast for the associated figures, comments, and other content not available in the audio format! Email us at icuedandtoddcast@gmail.com with any questions or suggestions! Thank you Mike Gannon for the intro and exit music!

Send us a Text Message (please include your email so we can respond!)Episode 78! We start our discussion of the trials that drop with ESICM with the much anticipated BICAR-ICU 2! Then we talk briefly about some changes to the SOFA score with the new SOFA-2 score. BICAR-ICU2: https://pubmed.ncbi.nlm.nih.gov/41159812/BICAR-ICU 2 (JAMA): https://jamanetwork.com/journals/jama/fullarticle/2840824SOFA-2: https://pubmed.ncbi.nlm.nih.gov/41159833/SOFA-2 (JAMA): https://jamanetwork.com/journals/jama/fullarticle/2840822If you enjoy the show be sure to like and subscribe, leave that 5 star review! Be sure to follow us on the social @icucast for the associated figures, comments, and other content not available in the audio format! Email us at icuedandtoddcast@gmail.com with any questions or suggestions! Thank you Mike Gannon for the intro and exit music!

Send us a Text Message (please include your email so we can respond!)Episode 77! We will start on ESICM coverage next episode. In this episode we talk about WFIT or "A Randomized Controlled Trial of a Post-ICU Telehealth Care Model" by Bakhru et al published in the blue journal September 2025! A long discussion but a good one!WFIT: https://pubmed.ncbi.nlm.nih.gov/40532205/Editorial: https://pubmed.ncbi.nlm.nih.gov/40700738/ICU Recovery Pilot: https://pubmed.ncbi.nlm.nih.gov/31385881/If you enjoy the show be sure to like and subscribe, leave that 5 star review! Be sure to follow us on the social @icucast for the associated figures, comments, and other content not available in the audio format! Email us at icuedandtoddcast@gmail.com with any questions or suggestions! Thank you Mike Gannon for the intro and exit music!

Send us a Text Message (please include your email so we can respond!)We were LIVE from the CHEST Annual Meeting 2025! Thanks to everyone who came out and stuck around to chat afterwards. We cover a lot of ground including some conference and Chicago related banter (~8 minutes if you wanted to skip to the learning!)High frequency oscillation: https://pubmed.ncbi.nlm.nih.gov/40983167/MELLOW: https://pubmed.ncbi.nlm.nih.gov/39800236/Continuous glucose monitoring: https://pubmed.ncbi.nlm.nih.gov/39956190/SAFE-ECMO: https://pubmed.ncbi.nlm.nih.gov/40081660/BASE: https://pubmed.ncbi.nlm.nih.gov/39971001/If you enjoy the show be sure to like and subscribe, leave that 5 star review! Be sure to follow us on the social @icucast for the associated figures, comments, and other content not available in the audio format! Email us at icuedandtoddcast@gmail.com with any questions or suggestions! Thank you Mike Gannon for the intro and exit music!

The hosts dive into melatonin's role in delirium prevention, spotlighting the intriguing MELLOW trial. They explore its creative acronym and share insights on trial feasibility and enrollment challenges. A meta-analysis suggests a modest benefit, while varying results across patient populations raise questions. The discussion also touches on the complexities of delirium management and the potential for nurse-driven protocols. Finally, practical considerations about sternal intraosseous access in trauma settings round out an engaging conversation.

Dive into the fascinating world of spontaneous breathing trials (SBTs) as the hosts explore the groundbreaking 1996 trial that revolutionized ICU practices. They discuss the risks of delaying extubation and reveal key findings from a recent study, highlighting barriers like procedures and staffing issues. Anecdotes about missed extubation opportunities add a personal touch. Plus, discover how simple notifications could streamline timely extubation decisions and enhance patient outcomes!

Send us a Text Message (please include your email so we can respond!)We are (were) LIVE at ACNP Critical Care Bootcamp 2025! Thank you to the organizers of the conference for inviting us do a live show and thank you to everyone who came out to listen! We talk about the PIC trial or "Adjunctive corticosteroids in non-AIDS patients with severe Pneumocystis jirovecii pneumonia" by Lemiale et al published in the Lancet Respiratory Medicine September 2025PIC (pubmed): https://pubmed.ncbi.nlm.nih.gov/40652952/PIC (LRM): https://www.thelancet.com/journals/lanres/article/PIIS2213-2600(25)00125-0/abstractIf you enjoy the show be sure to like and subscribe, leave that 5 star review! Be sure to follow us on the social @icucast for the associated figures, comments, and other content not available in the audio format! Email us at icuedandtoddcast@gmail.com with any questions or suggestions! Thank you Mike Gannon for the intro and exit music!

Send us a Text Message (please include your email so we can respond!)Episode 72! We continue talking about the articles from the CCR25 conference with UK-ROX or "Conservative Oxygen Therapy in Mechanically Ventilated Critically Ill Adult Patients" published in JAMA 2025 by Martin et al and TARGET-Protein or "Sodium bicarbonate therapy for patients with severe metabolic acidaemia in the intensive care unit" by Jaber et al in Lancet 2018.UK-ROX: https://pubmed.ncbi.nlm.nih.gov/40501321/UK-ROX (JAMA): https://jamanetwork.com/journals/jama/article-abstract/2835384TARGET-Protein: https://pubmed.ncbi.nlm.nih.gov/40495743/TARGET-Protein (JAMA): https://jamanetwork.com/journals/jama/article-abstract/2835302If you enjoy the show be sure to like and subscribe, leave that 5 star review! Be sure to follow us on the social @icucast for the associated figures, comments, and other content not available in the audio format! Email us at icuedandtoddcast@gmail.com with any questions or suggestions! Thank you Mike Gannon for the intro and exit music!

Send us a Text Message (please include your email so we can respond!)Episode 71! We continue talking about the articles from the CCR25 conference with FLUID or "A Crossover Trial of Hospital-Wide Lactated Ringer's Solution versus Normal Saline" published in NEJM 2025 by McIntyre et al and our old article is BICAR-ICU or "Sodium bicarbonate therapy for patients with severe metabolic acidaemia in the intensive care unit" by Jaber et al in Lancet 2018.FLUID: https://pubmed.ncbi.nlm.nih.gov/40503714/FLUID (NEJM): https://www.nejm.org/doi/10.1056/NEJMoa2416761BICAR-ICU: https://pubmed.ncbi.nlm.nih.gov/29910040/If you enjoy the show be sure to like and subscribe, leave that 5 star review! Be sure to follow us on the social @icucast for the associated figures, comments, and other content not available in the audio format! Email us at icuedandtoddcast@gmail.com with any questions or suggestions! Thank you Mike Gannon for the intro and exit music!