
ICU Ed and Todd-Cast
Two critical care guys walk into a recording studio and breakdown intensive care trials both old and new! We'll also do deep dives on specific topics important to practicing intensive care medicine and have special guests talking about their area of expertise! This podcast is made for educational purposes. The content provided in this podcast, and in any linked materials, is not intended and should not be construed as medical advice and should not be used to diagnose or treat any medical condition. We try to stay away from opinions but all opinions represent our own and not of any entity we work for. Please keep this in mind as you enjoy the podcast!
Latest episodes

Mar 12, 2024 • 53min
New: VENT-AVOID with Eddy Fan and Whitney Gannon
Listen to experts discuss VENT-AVOID, a technique to avoid invasive ventilation in COPD exacerbations. Explore the future of ECMO management and the challenges of clinical trials. Dive into the efficiency and risks of CO2 removal in medical procedures, clinical trial outcomes, and managing bleeding complications in ECMO and dialysis.

Feb 27, 2024 • 1h 3min
Old/Old/Old: VASST, VANISH, ATHOS-3
In this episode, the hosts dive into the world of vasopressors, focusing on vasopressin and angiotensin-2 in trials like VASST, VANISH, and ATHOS-3. They discuss the challenges of managing blood pressure, trial outcomes, and implications for clinical practice. The chapter also explores ethical debates, treatment strategies, and the efficacy of different pressors in critical care settings.

Feb 13, 2024 • 42min
Obs/Old: Invasive vs Non-invasive Blood Pressure and 65 Trial
Send us a Text Message (please include your email so we can respond!)Episode 31! This episode we talk first about invasive vs non-invasive blood pressures from an observational paper titled "Accuracy of Noninvasive Blood Pressure Monitoring in Critically Ill Adults" published in journal of Intensive Care Medicine by Haber et al and then for our old trial we further the discussion of blood pressure by talking about the 65 trial!Non-invasive vs invasive blood pressure: https://pubmed.ncbi.nlm.nih.gov/38215002/65 Trial: https://pubmed.ncbi.nlm.nih.gov/32049269/If you enjoy the show be sure to like and subscribe, leave that 5 star review! Be sure to follow us on the social @icucast for the associated figures, comments, and other content not available in the audio format! Email us at icuedandtoddcast@gmail.com with any questions or suggestions! Thank you Mike Gannon for the intro and exit music!

Jan 30, 2024 • 55min
SCCM: PROPHY-VAP and Mailbag
Guest Professor Dahyot-Fizelier discusses the study on Ceftriaxone for preventing pneumonia in brain injury patients. Other topics include SCCM conference, intubation timing, and steroids in ARDS.

Jan 16, 2024 • 48min
ATS vs ESICM ARDS Guidelines
Comparing and contrasting ATS and ESICM ARDS guidelines, exploring CPAP and high flow interventions, discussing corticosteroid and ECMO use, debating neuromuscular blockade benefits, controversy over recruitment maneuvers and high PEEP in critical care management

Jan 2, 2024 • 55min
New/Old: PRONECMO and EOLIA
Exploring the benefits of prone positioning during ECMO therapy for ARDS patients. Reflecting on the humility and challenges of critical care. Debating the use of medical terminology like 'Portuguese man award' and 'prone ECMO'. Delving into the efficacy of prone positioning and ECMO therapy for severe respiratory issues. Discussing the components and outcomes of the EOLIA study on ECMO therapy for ARDS. Analyzing the results of a clinical trial comparing ECMO to conventional treatment for severe ARDS.

Dec 19, 2023 • 47min
New/Old: NICO and Intubation timing
Send us a Text Message (please include your email so we can respond!)Episode 27! In this episodes we sit down to talk all about the "when" to intubate a patient centered around acute poisoning in the NICO trial or "Effect of Noninvasive Airway Management of Comatose Patients With Acute Poisoning: A Randomized Clinical Trial" published by Freud et al in JAMA November 2023. We ended up talk a lot about that so we cut our old article a little bit short and discuss a couple of JAMA articles about definitive airways in out of hospital cardiac arrestNICO: https://pubmed.ncbi.nlm.nih.gov/38019968/PART: https://pubmed.ncbi.nlm.nih.gov/30167699/Prehospital advanced airway: https://pubmed.ncbi.nlm.nih.gov/23321764/If you enjoy the show be sure to like and subscribe, leave that 5 star review! Be sure to follow us on the social @icucast for the associated figures, comments, and other content not available in the audio format! Email us at icuedandtoddcast@gmail.com with any questions or suggestions! Thank you Mike Gannon for the intro and exit music!

Dec 12, 2023 • 50min
New: ACORN with PulmPEEPs
Send us a Text Message (please include your email so we can respond!)This was easily our most requested article to discuss and for good reason - Eddie and Todd recently published the ACORN trial or "Cefepime vs Piperacillin-Tazobactam in Adults Hospitalized With Acute Infection" in JAMA October 2023. We recognize our bias as the first and last authors on the paper so we wanted to get some other smart people in the studio to balance us out so we partnered with Furf and Monty of PulmPEEPs for this episode. It is simul-dropping on their feed as well. Thank you to them for a great episode and the opportunity to talk about our trial!ACORN: https://pubmed.ncbi.nlm.nih.gov/37837651/If you enjoy the show be sure to like and subscribe, leave that 5 star review! Be sure to follow us on the social @icucast for the associated figures, comments, and other content not available in the audio format! Email us at icuedandtoddcast@gmail.com with any questions or suggestions! Thank you Mike Gannon for the intro and exit music!

Dec 5, 2023 • 45min
New/Obs: MINT and ICH related to transfusions
In this podcast, they discuss the MINT trial related to restrictive transfusion strategies in heart attacks and an observational study on intracerebral hemorrhage in blood donors. They cover the implications for patient care, unique medical cases, and explore transfusion thresholds in critical care and oncology. The hosts compare different trials, delve into the complexities of interpreting trial results, and explore the risks of cerebral hemorrhages in transfusion recipients. They also touch on linguistics, career viability, and social media engagement.

Nov 21, 2023 • 56min
New/New/New: COVID Trials (ESICM Part 2)
Send us a Text Message (please include your email so we can respond!)Episode 24! Three trials about COVID were published with ESICM which we talk about all three here. COVID has been decreasing in prevalence in our ICU at least so we anchor our discussion around what we can learn from these trials about ARDS in general or what we can carry forward to future pandemics compared to our typical "Are we using this in our practice".Simvastatin: https://pubmed.ncbi.nlm.nih.gov/37888913/Vitamin C: https://pubmed.ncbi.nlm.nih.gov/37877585/Convalescent Plasma: https://pubmed.ncbi.nlm.nih.gov/37889107/If you enjoy the show be sure to like and subscribe, leave that 5 star review! Be sure to follow us on the social @icucast for the associated figures, comments, and other content not available in the audio format! Email us at icuedandtoddcast@gmail.com with any questions or suggestions! Thank you Mike Gannon for the intro and exit music!
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