ICU Ed and Todd-Cast

The hosts discuss the CCR24 conference, stress ulcer prophylaxis in ventilated patients, conflicting data in critical care, comparison of pre-oxygenation methods, sedation options, ivermectin use for COVID-19, steroids for pneumonia, and upcoming presentations on various treatment options in critical care.

Kevin Gibbs, presenter of the PREOXI trial, talks about challenges in airway management, variability in medical practices, and the importance of pre-oxygenation techniques. The podcast explores the debate over the trial acronym, compares pre-oxygenation methods, and discusses the findings of the Intube study. It delves into the benefits of pre-procedural non-invasive ventilation and the implementation challenges in emergency tracheal intubations.

In this podcast, they discuss steroids in septic shock from community acquired pneumonia, the challenges of intubation timing, and driving pressure in critical care. They analyze the Approach trial, share insights on subgroup analysis, and debate the benefits of steroid administration. The hosts also joke about a triathlon, announce upcoming conferences, and highlight the importance of evaluating secondary analyses.

ATS conference insights include discussions on asthma content, post-ICU recovery, breathing exercises for survivors, intubation in newborns, and personalized treatment effects. Light-hearted banter about scenarios and sponsorship opportunities adds a fun touch to the podcast.

Send us a Text Message (please include your email so we can respond!)Episode 37! In this episode we talk about glycemic control in the ICU. We liked the flipped script and so we're again going old article first. NICE-SUGAR or "Intensive versus conventional glucose control in critically ill patients" was published in NEJM 2009 and then we talk about TGC-Fast or "Tight Blood-Glucose Control without Early Parenteral Nutrition in the ICU" published NEJM September of 2023 NICE SUGAR: https://pubmed.ncbi.nlm.nih.gov/19318384/TGC-Fast: https://pubmed.ncbi.nlm.nih.gov/37754283/If you enjoy the show be sure to like and subscribe, leave that 5 star review! Be sure to follow us on the social @icucast for the associated figures, comments, and other content not available in the audio format! Email us at icuedandtoddcast@gmail.com with any questions or suggestions! Thank you Mike Gannon for the intro and exit music!

Explore the benefits of using tranexamic acid in managing upper gastrointestinal bleeding in cirrhosis patients based on the HALT-IT study findings. Delve into the use of tranexamic acid in critical care, analyzing the design, outcomes, and implications for patient groups. Discuss the enrollment triggers for drug use post-HALT-IT study and interpret relative risk increase in GI bleed with cirrhosis for accurate treatment decisions.

Send us a Text Message (please include your email so we can respond!)Episode 35! In this episode we talk about extubation practices with "Effect of aggressive vs conservative screening and confirmatory test on time to extubation among patients at low or intermediate risk: a randomized clinical trial" published in Intensive Care Medicine by Hernandez et al. We then talk about an observation study by Zarrabian et al published in the Blue Journal "Liberation from Invasive Mechanical Ventilation with Continued Receipt of Vasopressor Infusions".SPEED UP: https://pubmed.ncbi.nlm.nih.gov/38353714/Extubation on Pressors: https://pubmed.ncbi.nlm.nih.gov/35107416/If you enjoy the show be sure to like and subscribe, leave that 5 star review! Be sure to follow us on the social @icucast for the associated figures, comments, and other content not available in the audio format! Email us at icuedandtoddcast@gmail.com with any questions or suggestions! Thank you Mike Gannon for the intro and exit music!

Send us a Text Message (please include your email so we can respond!)Episode 34! In this episode we talk about oxygen targets! Specifically we go over the two oxygen target analyses that were published simultaneously with ISICEM. We spend most of our time with HOT-COVID published by Nielson et al and then dip a little into individualized treatment effects of oxygen targets published by Buell et al - both published in JAMA March 2024. The latter is a complex topic and we hit some of the high points but please reach out to us if you want a more in depth discussion!HOT-COVID: https://pubmed.ncbi.nlm.nih.gov/38501214/Individualized Treatment Effects: https://pubmed.ncbi.nlm.nih.gov/38501205/If you enjoy the show be sure to like and subscribe, leave that 5 star review! Be sure to follow us on the social @icucast for the associated figures, comments, and other content not available in the audio format! Email us at icuedandtoddcast@gmail.com with any questions or suggestions! Thank you Mike Gannon for the intro and exit music!

Listen to experts discuss VENT-AVOID, a technique to avoid invasive ventilation in COPD exacerbations. Explore the future of ECMO management and the challenges of clinical trials. Dive into the efficiency and risks of CO2 removal in medical procedures, clinical trial outcomes, and managing bleeding complications in ECMO and dialysis.

In this episode, the hosts dive into the world of vasopressors, focusing on vasopressin and angiotensin-2 in trials like VASST, VANISH, and ATHOS-3. They discuss the challenges of managing blood pressure, trial outcomes, and implications for clinical practice. The chapter also explores ethical debates, treatment strategies, and the efficacy of different pressors in critical care settings.