

The Gillett Health Podcast
Kyle Gillett and James O'Hara
Health Optimization
Episodes
Mentioned books

Dec 12, 2025 • 14min
New Hair Loss Medication
Exciting developments in hair loss treatment are on the horizon with a new medication, PP405, showing promising results. The hosts dive into how it targets scalp stem cells to potentially restore hair follicles. They discuss the implications of a 31% density increase and the importance of context in interpreting study data. Concerns about non-responders and the study's timeframe are raised, along with the caution against using unregulated compounds. Plus, they explore other topical options in the hair-loss arena!

Dec 5, 2025 • 12min
Trump Got an MRI?
Dr. Gillett and James O'Hara dive into President Trump's MRI, questioning its purpose and exploring the ethics of full-body scans. They discuss the downsides of routine screening, like false positives and the burden of incidental findings. Privacy concerns around public release of presidential health data are raised, along with debates on pricing transparency in medical imaging. The hosts advocate for cash-pay options and emphasize that routine MRIs aren't typically recommended, all while inviting listeners to share their own experiences.

Nov 25, 2025 • 33min
Doctor ranks his favorite steroids
The hosts rank anabolic steroids by health risk and benefits, using a tier-list method. They dive into testosterone sources and the pros and cons of compounded products. The conversation covers DHEA's unpredictable effects, nandrolone's anabolic profile, and the risks associated with oxandrolone. They discuss trenbolone's potency and harsh side effects, along with the limited availability of Primobolan. Additionally, listeners learn about the risks of Winstrol and the promise of SARMs versus street products.

6 snips
Nov 14, 2025 • 15min
Are GLP1s making us all weak?
Explore the controversial world of GLP-1s and their effects on health. The hosts tackle dramatic claims about GLP-1s accelerating aging, while cautioning against misuse by influencers. They emphasize the importance of strength training and protein intake to prevent muscle loss during weight loss. Discussing the limited data on children, they highlight potential risks for young users. The conversation pivots to individualized treatment and the mixed evidence on GLP-1s improving health outcomes in older adults, urging a tailored approach.

9 snips
Nov 7, 2025 • 20min
The Rock is on steroids?
The hosts dive into The Rock's heart scan and steroid use rumors, discussing the nuances of cardiac imaging. They highlight the risks of low HDL as a steroid marker and the importance of clinician reviews over AI reports. A fascinating debate unfolds on the line between testosterone replacement therapy and anabolic steroids. They also explore the challenges celebrities face in accessing quality preventive care, the value of informed consent, and the need for tailored screening for bodybuilders. Overall, it's a thought-provoking look at health, fitness, and misconceptions in the media.

9 snips
Oct 27, 2025 • 17min
This one thing is clogging arteries
Discover the intriguing new data on lean mass hyper-responders and its implications for heart health. Dive into the differences between total plaque scores and the CLEARLY method, revealing why accurate analysis matters. Learn about the clinical significance of plaque progression rates and how dietary adjustments can modify risk factors. The hosts discuss the effects of imaging on participants' long-term care decisions and tackle radiation concerns with monitoring techniques. Lastly, get a sneak peek at future analyses in plaque progression.

5 snips
Oct 17, 2025 • 23min
The Low Testosterone Crisis
Dive into the low testosterone crisis with intriguing insights on historical trends and modern lifestyle factors. Discover how obesity, sleep apnea, and even smoking influence testosterone levels in unexpected ways. The hosts dissect decade-by-decade data, tackling the complexities of interpreting studies and health impacts. They share practical tips on testing and lifestyle adjustments to combat declining testosterone, while noting global patterns and teasing a discussion on the fertility crisis. It's an eye-opening conversation about men's health!

Oct 10, 2025 • 18min
How To Do Steroids Safely
James O'Hara, a nurse practitioner, shares his insights on using nandrolone for recovery after pectoral surgery. He discusses his personal recovery stack, including estradiol and peptides, and the dos and don'ts of anabolic therapy. James reveals the importance of monitoring health markers like hematocrit and explains his experience with hormone side effects. He emphasizes the role of nutrition in muscle preservation and offers valuable takeaways for safe recovery strategies. Tune in for expert advice on hormonal management!

Oct 8, 2025 • 16min
Most Brutal Gym Deaths Reaction
Dr. Gillett and David dive into shocking incidents of gym fatalities. They explore the risks of cardiac issues while using treadmills and the importance of proper screening. The duo highlights the dangers of faulty equipment, safety protocols for squats and bench presses, and the perks of wearables for early warning signs. They address the perils of ego lifting and the need for safety measures during high-stakes lifts. A chilling reminder about the limits of our bodies and the crucial role of safety in workouts keeps the conversation engaging.

14 snips
Sep 30, 2025 • 30min
Shoulder Pain: Is surgery always the answer?
Dr. Dan Gurley, an orthopedic surgeon specializing in shoulder injuries, shares insights on various surgical approaches and treatment options. He discusses the pros and cons of shoulder surgeries, especially for older adults, and highlights the importance of tailored imaging. The conversation delves into innovative topics like AI predictions for injuries and the potential of peptides in healing. Dan also emphasizes the significance of proper training to prevent injuries, especially in athletes, and offers advice on managing common concerns like AC joint inflammation.


