Two Onc Docs

Explore the world of non-melanoma cutaneous malignancies such as squamous cell skin cancer and basal cell carcinoma. Get insight into staging, diagnosis, and treatment options, including the importance of thorough workups for suspicious lesions. Learn about high-risk skin cancers, treatment options for unresectable or metastatic cases, and the importance of complete tumor removal for basal cell carcinomas.

Exploring the diagnosis, risk factors, and demographics of malignant pleural mesothelioma. In-depth discussion on BAP1 gene mutation, cancer risks, screening recommendations, symptoms, and diagnostic process. Detailed explanation of staging pleural mesothelioma based on tumor size and lymph node involvement. Treatment strategies for stage 1-3 epithelioid pleural mesothelioma including induction chemotherapy and surgical procedures. Comprehensive treatment strategies for malignant mesothelioma tailored to different stages and histologies.

Exploring the vital role of Bone Modifying Agents like bisphosphonates and Denosumab in reducing skeletal complications for cancer patients. Discussing the impact of breast, prostate, and lung cancers on bone metastasis. Stressing the importance of creatinine clearance cutoffs, dental clearance, and monitoring for side effects prior to treatment. Highlighting the efficacy of these agents in managing metastatic diseases and rare bone sarcomas.

This podcast explores acquired causes of underproduction anemias, including iron deficiency, vitamin B12 and folate deficiencies, anemia of chronic disease, anemia of pregnancy, and rarer causes. It covers diagnostic methods, lab results, iron supplementation, micronutrient deficiencies, and treatment options.

This podcast focuses on cancers of unknown primary (CUP), discussing the work-up, diagnostic markers, molecular testing, and treatment options. They explore the use of immunohistochemistry and molecular testing for diagnosis and treatment, including specific markers for different types of cancer and the importance of identifying targetable mutations.

The podcast discusses the presentation, diagnosis, and treatment of Mantle Cell Lymphoma. They cover the workup, diagnostic criteria, and treatment options for both limited stage and advanced cases. They also explore various treatment options based on patient age and fitness, including stem cell transplant and agents for relapsed or refractory cases.

This podcast explores Adrenocortical Carcinoma, a rare and aggressive tumor. Topics discussed include symptoms, imaging features, staging, treatment options, radiation, and monitoring for the tumor. Key pearls and treatment strategies are also provided, including hormonal evaluation, surgery, and the importance of clinical trials.

This podcast discusses Hairy Cell Leukemia, including its symptoms, diagnosis, and treatment options. It covers the diagnosis process, genetic mutation in Hairy Cell Leukemia, treatment approaches, and prophylaxis for the disease.

Dr. Tom Powles and Dr. Brian Rini discuss 2023 updates for metastatic bladder cancer, including staging, treatment options, and variant histologies. They highlight the efficacy and adverse event profile of single agent pembrolizomab and mabidotin. The podcast also covers new drugs in oncology and treatment options for urethral carcinoma. Additionally, they discuss less common histologic types of bladder cancer and the challenges of variant histologies for personalized treatment approaches.

Dr. Tom Powles and Dr. Brian Rini discuss 2023 updates for localized bladder cancer, including diagnostic workup, staging, and treatment options. They share mixed opinions on a trial and challenges in therapy, express skepticism towards PET scans, and explore various treatment options. Exciting insights from the urologic oncology experts!