Two Onc Docs
Oncologic Emergencies
Jul 15, 2024
This podcast delves into high-yield topics on oncologic emergencies for new fellows and residents, covering brain metastases, hypercalcemia, cord compression, and SVC syndrome. They discuss management strategies like steroids, fluids, bisphosphonates, and RANK L inhibitors, emphasizing the importance of timely interventions for optimal patient care.
12:27
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Quick takeaways
- Symptomatic brain metastases may require steroids and systemic therapy with blood-brain barrier penetration.
- Hypercalcemia treatment involves fluid expansion, bisphosphonates, and dental clearance before bisphosphonate use.
Deep dives
Management of Brain Metastases and Treatment Approaches
Symptomatic brain metastases require consideration of steroids. Prophylaxis with various medications is essential for patients on high-dose steroids. Treatment options for single versus multiple brain metastases include resection and SBRT or whole brain radiation, depending on the case. In certain cancers, systemic therapy with high blood-brain barrier penetration can be prioritized over local treatments.
