Two Onc Docs

Dive into the nuances of hematology and oncology board exams with valuable insights. Learn effective study strategies, including prioritizing high-yield topics and using cheat sheets. Discover staging and treatment options for non-small cell lung cancer, as well as the latest in breast cancer therapy. Gain clarity on critical conditions like von Willebrand disease and congenital bone marrow syndromes. The hosts also discuss research ethics and supportive care essentials, ensuring you're fully prepared for the challenge ahead!

Discover the intriguing link between porphyrias and vampire folklore, with tales of photosensitivity and garlic aversion that inspired myths! Learn about key porphyrias, their triggers, and how they're diagnosed and treated. Explore the management of chronic forms and the rare congenital types. Whether you're preparing for exams or fascinated by these mysterious diseases, this conversation provides crucial insights and fun Halloween connections!

Delve into cutting-edge advancements in metastatic breast cancer treatment. Frontline options for ER/PR-positive patients and the intricacies of CDK4/6 inhibitors are discussed. Key insights on HER2-positive regimens reveal exciting trial data. Triple-negative challenges are tackled with biomarker testing and promising therapies. Learn about the role of bone protective agents in care strategies. The hosts wrap up with practical treatment algorithms and reminders for optimal patient management.

Explore the latest in localized breast cancer treatments with 2025 updates! Discover when radiation can be skipped after surgery and the role of neoadjuvant therapies. Delve into the complexities of treating triple negative disease, including chemotherapy and the use of carboplatin. Understand hormonal therapies for ER/PR positive cases, their potential side effects, and the importance of genomic testing. Plus, insights on managing breast cancer in men and during pregnancy provide a comprehensive view of contemporary care options.

October marks Breast Cancer Awareness Month, making this a timely discussion. Key topics include breast cancer risk factors, when to get genetic testing, and screening recommendations for high-risk individuals. They delve into the management of LCIS and DCIS, detailing treatment options like mastectomy versus lumpectomy. Insights on chemoprevention, tamoxifen's side effects, and the challenges of rare breast histologies are also explored. Plus, learn the basics of staging and when axillary dissection is necessary.

Get ready to dive into the complex world of esophageal and gastroesophageal junction cancers! Discover the symptoms like dysphagia and hoarseness, and learn how to differentiate cancer types based on location. Uncover the risk factors for squamous versus adenocarcinoma. The discussion also covers the latest diagnostic techniques and staging criteria. Explore treatment options from endoscopic resection to cutting-edge chemotherapy regimens. Don't miss the insights on managing metastatic disease and key trials shaping future therapies!

Explore the world of Immune Thrombocytopenia Purpura (ITP) in this enlightening discussion. Learn about the mechanisms of antibody-mediated platelet destruction and the factors that can lead to this condition. Discover the clinical signs to watch for and the comprehensive diagnostic approach used by experts. The conversation dives into treatment options, from steroids to advanced therapies like TPO agonists and rituximab. It's a crucial update packed with insights relevant for heme consults and board reviews.

Dive into the intricate world of bone sarcomas as the hosts break down vital topics like diagnosis, staging, and treatment strategies. Explore the unique characteristics of osteosarcoma and Ewing's sarcoma, highlighting the importance of personalized therapies. Discover how genetic mutations influence treatment plans and the critical role of surgical interventions. With a focus on the latest chemotherapy protocols and emerging systemic treatments, this discussion sheds light on a challenging yet fascinating area of oncology.

Delve into the latest insights on soft tissue sarcomas, featuring new FDA approvals and evolving diagnostic challenges. Discover the complexities of this rare category of tumors, which represent just 1% of adult cancers and include both noncancerous and aggressive forms. Learn about treatment strategies for various subtypes, including desmoid tumors and Kaposi's sarcoma, highlighting innovative surgical and chemotherapy advancements. The emphasis is on a multidisciplinary approach to enhance patient outcomes.

Dive into the world of Thrombotic Thrombocytopenic Purpura (TTP) with high-yield facts on its mechanisms, symptoms, and treatment strategies. Explore the urgency of prompt diagnosis and how plasmapheresis can save lives. Learn about Hemolytic Uremic Syndrome (HUS), especially its impact on children and the critical need for early intervention. The discussion covers risk factors and treatment options, making it essential knowledge for both medical professionals and anyone interested in understanding these serious conditions.