Two Onc Docs

Porphyria

10 snips
Oct 27, 2025
Discover the intriguing link between porphyrias and vampire folklore, with tales of photosensitivity and garlic aversion that inspired myths! Learn about key porphyrias, their triggers, and how they're diagnosed and treated. Explore the management of chronic forms and the rare congenital types. Whether you're preparing for exams or fascinated by these mysterious diseases, this conversation provides crucial insights and fun Halloween connections!
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INSIGHT

Porphyrias And Vampire Lore

  • Porphyrias can explain vampire folklore via photosensitivity, skin tightening, pale skin, garlic aversion, and red urine.
  • These visible and behavioral features historically mimicked vampiric traits and fueled myths.
ADVICE

Look For Trilogy Of Symptoms

  • Check for photosensitivity, neurologic symptoms, and GI pain when porphyria is suspected.
  • Ask about medication, smoking, and other environmental triggers that worsen symptoms.
INSIGHT

Two Useful Clinical Categories

  • Porphyrias group into acute porphyrias (neurovisceral attacks) and chronic cutaneous porphyrias (skin phototoxicity).
  • This division guides which labs and treatments you prioritize in workup and management.
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