
Into the Impossible With Brian Keating Sir Roger Penrose | The Emperor’s New Mind: Consciousness & Computer | INTO THE IMPOSSIBLE Podcast (#311)
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Apr 11, 2023 Nobel-winning physicist Roger Penrose explores whether consciousness can be explained by computers, and why quantum physics may hold a missing piece. The conversation moves from microtubules and mathematical reality to symmetry, falsifiable predictions, and the universe’s far-future fate.
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Understanding Transcends Computation
- Roger Penrose argues human understanding transcends computation based on Gödel-style reasoning about mathematical proof and comprehension.
- He claims our ability to see the truth of Gödel statements shows understanding is non-algorithmic and requires physics beyond standard quantum theory.
Hameroff Letter Sparked Orch-OR Collaboration
- Penrose recounts Stuart Hameroff writing to him about microtubules after reading The Emperor's New Mind, which shifted his thinking on biological quantum coherence.
- That exchange led to their collaboration and the orchestrated objective reduction (Orch-OR) hypothesis linking microtubules to consciousness.
Microtubule Symmetry Could Shield Coherence
- Microtubule A-lattice symmetry could create degenerate quantum states with a band gap that helps preserve coherence.
- Penrose highlights the Jahn–Teller–style idea that high symmetry isolates a low quantum level from decohering interactions.

