

Into the Impossible With Brian Keating
Big Bang Productions Inc.
Think like a physicist. Wonder like a human. Into the Impossible is where Cosmic Conversations happen — uniting Nobel Prize winners, iconoclasts, authors, and technologists to explore reality’s deepest questions. From AI to aliens, from biophysics to the brain, from the cosmos to the multiverse, Brian Keating, Chancellor’s Distinguished Professor of Physics at UC San Diego covers it all.If you’ve ever asked What’s out there? or What’s next?, this is where curiosity meets clarity.Learn to think like this. 🎙 Full episodes, notes & more: briankeating.com/podcast
Episodes
Mentioned books

26 snips
Nov 15, 2025 • 1h 50min
Avi Loeb Fights Back: Response to Brian Cox & the 3I/ATLAS Critics
Avi Loeb, a Harvard astrophysicist and director of the Galileo Project, dives into the captivating complexities of the interstellar object 3I/ATLAS. He discusses its unusual jets and spectral changes that defy traditional comet models. Addressing critiques from figures like Brian Cox, Loeb emphasizes the importance of scientific humility and open inquiry. He explores whether the object's movements suggest natural sublimation or technological propulsion, highlighting the implications for the future of scientific discourse.

Nov 11, 2025 • 27min
Krauss: “DESI Is Wrong: Dark Energy Isn’t Changing”
Lawrence Krauss, a renowned theoretical physicist and bestselling author, shares his insights on the latest findings in dark energy and critiques the hype surrounding it, asserting that results from DESI may be overstated. He discusses the evolution of his own beliefs in vacuum energy and the Higgs boson, emphasizing science's adaptability. Krauss also explores the limitations of quantum gravity theories and the potential role of AI in discovering new laws of physics, noting its current shortcomings and future possibilities.

7 snips
Nov 7, 2025 • 1h 7min
How to Talk to Aliens (ft. Daniel Whiteson)
In this engaging discussion, particle physicist and science communicator Daniel Whiteson explores whether aliens could communicate through physics. He provocatively questions if we would even recognize their language, which could derive from billions of years of advanced thought. The conversation delves into the Drake Equation, the potential role of AI as a form of intelligence we might encounter, and how different sensory perceptions could lead to varying interpretations of the universe. Additionally, Daniel reflects on using art to make complex ideas accessible.

4 snips
Nov 5, 2025 • 1h 19min
Physicist Explains UFOs, the Moon Landing, and the Case for God's Existence | Real Talk with Marissa Streit
Join Marissa Streit, CEO of PragerU, as she delves into cosmic mysteries with a renowned physicist. They discuss the tantalizing possibility of UFOs and the skepticism surrounding them, questioning government secrecy and public belief. The conversation touches on the moon landing, debunking myths with scientific evidence. Brian shares his journey from childhood stargazer to tackling big questions in faith and science, emphasizing humility while exploring the universe’s origins and our place within it.

Nov 4, 2025 • 32min
Was The Moon Landing A HOAX? (ft. Kim Kardashian, Candace Owens, & Bart Sibrel)
In this engaging discussion, Candace Owens, a sharp political commentator, and Bart Sibrel, a fervent moon landing skeptic, have their controversial claims scrutinized. Brian Keating tackles the infamous questions around the moon landing, addressing why the flag appears to move, how astronauts navigated the Van Allen belts, and the true reasons we haven't returned to the Moon. He also highlights evidence supporting the Apollo missions, from independent tracking to lunar rocks, emphasizing the importance of scientific literacy in debunking conspiracy theories.

27 snips
Nov 1, 2025 • 1h 38min
Avi Loeb's WARNING: Watch Out for THIS When 3i/ATLAS Nears The Sun!
Avi Loeb, a Harvard astrophysicist and director of the Galileo Project, joins to explore the enigmatic interstellar object 3I/ATLAS as it nears the Sun. He discusses potential signatures of its composition and the implications of its unusual behaviors, like abrupt brightening. Loeb highlights debates over its classification—natural comet or technological artifact—and the challenges of data access from NASA. He stresses the need for careful monitoring and collaboration to understand the mysteries of such objects, hinting at a future filled with surprising cosmic revelations.

26 snips
Oct 31, 2025 • 1h 17min
90% of Ancient Humans Vanished. We Reconstructed Their History (ft. David Reich)
David Reich, a Harvard geneticist renowned for his groundbreaking work in ancient DNA, delves into the complexities of human history. He reveals that a staggering 90% of ancient populations disappeared in mere centuries, leaving behind ghost civilizations like those who built Stonehenge. The conversation explores how genetic data uncovers our interconnected past, the fascinating ways ancient DNA is extracted, and the impact of Neanderthals and Denisovans on modern humans. Reich emphasizes that cultural myths often mirror real historical events, weaving a rich tapestry of our shared ancestry.

12 snips
Oct 28, 2025 • 51min
Could Biological Robots Heal Us from the Inside? | Michael Levin
In this enlightening discussion, Michael Levin, a distinguished biologist at Tufts University, explores the fascinating world of bioelectricity and Xenobots—living robots made from frog cells. He shares how these simple organisms can spontaneously heal brain tissue and even replicate through self-organization. Levin challenges our understanding of life, discussing the role of electricity in biological cognition and the potential of anthrobots, human cells designed to heal. This conversation reveals the intriguing intersection of biology, consciousness, and engineering.

9 snips
Oct 21, 2025 • 41min
Did We Detect Dark Matter… or Fool Ourselves?
Kaixuan Ni, a leading experimental physicist from UC San Diego focused on dark matter detection, discusses groundbreaking work in the field. He highlights liquid xenon detectors that fingerprint atomic collisions, revealing potential insights into dark matter and how these technologies can also monitor nuclear reactors. The debate around the DAMA/LIBRA experiment’s unconfirmed findings sparks intrigue. Kaixuan shares unexpected discoveries like solar neutrinos and rare nuclear decays, illustrating how the search for dark matter intertwines with vital global safety efforts.

4 snips
Oct 17, 2025 • 1h 13min
Will this NEW Scientific Breakthrough Make Us Immune to Everything? | George Church
George Church, a Harvard genetics professor and synthetic biology pioneer, discusses his groundbreaking achievement of making living cells immune to every virus on Earth. By simply removing certain genetic letters, Church’s team has created a virus-proof cell, promising revolutionary advancements in medicine. He explores the potential to engineer human cells for virus resistance, the ethical considerations involved, and even dreams of de-extinction and gene-edited astronauts for Mars missions. It's a fascinating blend of science fiction and reality.


