In Search of Insight Is NAD+ The Secret To Longevity? What Are Sirtuins?
03:08:14
NAD+ and its Biosynthesis
- NAD+ is vital for numerous bodily functions, interacting with about 300 enzymes and playing a crucial role in energy production.
- It has multiple biosynthesis pathways, including the denovo, Preiss-Handler, and salvage pathways, each utilizing different precursors.
Mimicking Ancestral Food Stress
- Combat modern food access by intentionally introducing stress through fasting or calorie restriction.
- Skipping meals or reducing calorie intake can mimic ancestral food insecurity, boosting NAD+ and sirtuin activity.
Emil's Fasting Experience
- Emil, while beta-testing an NAD+ stack, experienced increased energy and suppressed hunger while fasting.
- Taking the stack fasted in the morning allowed him to fast for 24 hours without hunger, suggesting NAD+'s potential role in appetite control.
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Introduction
00:00 • 3min
Beta Ectasteron - A Proper Dose of Beta Ectosteron
02:36 • 4min
Libido Boosting Effects From Betatoson
06:10 • 2min
Is R Ala a Good Alphalopoic Acid Supplement?
07:58 • 3min
Horny Goat Weed 50 % Icarin Powder
11:02 • 2min
What Is Na D Plus and What Is It Used For?
13:14 • 3min
How to Make an 80 Plus in 30 Seconds
16:28 • 3min
How to Get Nad Plus From Enidy Plus
19:23 • 5min
Nitin Ribeside Supplementation
24:38 • 4min
Enity Plus and Its Functions
28:59 • 4min
Enity Plus
33:26 • 3min
What Does Fasting Do to Your Cells?
36:46 • 2min
Stress and the Benefits of Supplementation
38:51 • 5min
Using Fasting as a Tool for Optimizing Our Health
44:07 • 2min
The Effects of Stress in Plants
46:29 • 4min
Is There a Circadian Rhythm?
50:49 • 1min
Boosting the N 80 Plus in the Morning
52:17 • 5min
Is There a Way to Control Cordisal?
56:51 • 4min
What Are the Hall Marks of a Person With Healthy and 80 Plus Levels?
01:00:35 • 4min
The Long Term Effects of Taking Nity Plus Precursors
01:04:20 • 5min
The Effects of Agty Plus on Fertility
01:09:45 • 3min
Are Anyty Plus Precursors Beneficial to Fertility?
01:12:40 • 2min
The Sertuman Activator Resvere Troll
01:14:59 • 4min
Anima Nn R - What Are the Best Products to Up Regulate Certin Activity?
01:19:06 • 3min
Allte Leserts Are Equally Important
01:21:49 • 3min
Magnolia Bark Extract Is a Very Good Activator of Cert Three Proteins
01:25:06 • 3min
Is Hinochiol a Stimulant?
01:28:21 • 2min
Dope Men Reoptic Inhibitor
01:30:15 • 3min
Can Resvertrol Help in Certaien Activation?
01:32:57 • 2min
Is There a Better Way to Lower Glucos Levels?
01:35:14 • 2min
Is There Anything You Would Like to Add to the Ultimate Plus?
01:37:25 • 3min
How to Optimize Your and Plus Levels
01:40:28 • 2min
Can Younger People Experience the Benefits of an 80 Plus Booster?
01:42:40 • 2min
Is It a Good Idea to Take Anamenan N R With Tmg?
01:44:53 • 2min
Is Adanine a Bottleneck for Anidy Plus?
01:46:44 • 3min
Taking Anamen or an R to Avoid Insomnia?
01:49:33 • 2min
Is Enemen Really Required?
01:51:16 • 3min
Interactions With Anyty Plus Precursors?
01:53:54 • 3min
Increasing Anity Plus With Nicotinic Acid, Niacin, or Niocen Mite?
01:56:32 • 2min
Can Curecedent Work With Enity Plus Precursors?
01:58:12 • 2min
Is There a De Novo Anid Plus Precursor?
02:00:09 • 2min
Animen Dosing and Fertility in Mice
02:01:50 • 3min
The Effects of Dplus Precursors on Fertility
02:04:24 • 2min
Does Na D H Become Oxidized or Otherwise Degrade Very Quickly and Easily?
02:06:23 • 2min
Do Niasin Indirectly Increase Anity Plus?
02:07:54 • 3min
Is Animen Supplementation Beneficial for a Trained Not Aging?
02:11:23 • 2min
Glycosis
02:13:46 • 2min
Apigenin Dosage - What Dose Is Best With Anamen?
02:15:35 • 3min
What Age Should One Begin Taking Anihty Plus?
02:18:33 • 2min
Looking Younger Than 20?
02:20:17 • 2min
Are There Any Benefits to Supplementing With Nity Plus Precursors?
02:22:46 • 2min
How Does Fasting Affect Aneht Plus Levels?
02:24:57 • 5min
Is Enmen Better at Increasing D Plus Levels Than Amen?
02:29:31 • 3min
Is Sublingal a Viable Delivery Method for N M N N N R?
02:32:20 • 2min
Dosage of Enteric Coated Tablets and Powdered Anamen?
02:34:11 • 3min
Is It Better to Take Anamen and an R Together?
02:37:28 • 3min
How Long Should I Wait Before a Meal?
02:40:30 • 3min
Is Nmen Causing Lethargy or Tiredness?
02:43:19 • 4min
Are There Any Potential Down Sides to Raising Enity Plus Levels in the Aged?
02:47:25 • 3min
Dosing Ranges Really Work?
02:50:23 • 3min
Do Exogenous Supplementation of Enity Plus Increased Compounds Lead to Homeostatic Adjustment?
02:53:02 • 6min
How to Increase Anity Plus?
02:58:52 • 3min
Is There Anything That Could Undercut the Effectiveness of Increasing Anity Plus Levels?
03:01:35 • 3min
Are There Any Sub Populations That Should Avoid Raising Enity Plus Levels?
03:04:15 • 2min
In Search of Insight Podcast
03:06:05 • 2min
NAD+ is an endogenous compound that is responsible for cell activity, brain health, fertility, aging, and many more essential functions in our bodies. So how do we maintain healthy levels of NAD+ as we age, and what are the best strategies for keeping energy levels, mood, and cognition in tip-top shape for the long haul? This month on the In Search of Insight podcast, your hosts Emiel and Erika break down what NAD+ is, its biosynthesis pathways, and how supplementation can support healthy NAD+ levels as we age. This month on episode #009, dive into an exciting conversation and learn about:
-The biosynthesis pathways for NAD+
-How NMN and NR work together for optimal NAD+ support
-The synergism between Sirtuins and NAD+
-Why fasting is crucial for maintaining NAD+ levels
-Who can benefit from supplementing NAD+ precursors
-Fertility, cognition, metabolism, and strength benefits from NAD+
Be sure to subscribe to the In Search of Insight podcast on your favorite streaming platforms, and join a community of like-minded nootropics geeks just like you on Reddit at r/NootropicsDepot.