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Immune
Immune 66: COVID-19 immune memory - what you need to know
Apr 4, 2023
Immunology experts discuss immune memory to SARS-CoV-2 and COVID-19 vaccines, emphasizing CD8 T cells' role, different vaccine responses, epitope recognition, B cell longevity, booster efficacy debates, ethical obligations of billionaires, and the importance of knowledge sharing for vaccine development.
01:30:07
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Quick takeaways
- Memory CD8 T cells provide long-term immunity post-SARS-CoV-2 infection.
- B cell memory against future variants is long-lasting and influenced by disease severity.
Deep dives
Robust Immune Memory to SARS-CoV-2: Insights from Podcast Episode
The immune response to SARS-CoV-2 infection and vaccines has established benchmark levels of memory in human immunology, with extensive data on human antigen-specific immune responses. Studies indicate a significant presence of memory CD8 T cells providing long-term memory against the virus, lasting notably over 6 months, even showing potential for years. The hybrid immunity from vaccination and infection demonstrates similarities in generating memory responses, with a notable presence of spike-specific memory CD8 T cells in individuals over time.
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