Understanding Immune Memory in COVID-19

This chapter delves into various aspects of immune memory in COVID-19, including the challenges of using PD-1 as a marker for exhausted T cells and the lack of detectable SARS-CoV-2-specific memory CD-8 responses in some cases. The discussion also touches on the testing of peptides across viral open reading frames, implications of low CD8 responses in hospitalized COVID-19 cases, and the importance of CD8 cells in controlling infections like COVID-19.