Exploring Immune Memory and Vaccine Efficacy

The chapter delves into immune memory differences between infections with viremic stages and respiratory mucosal infections, comparing COVID-19 and influenza vaccines. It discusses the adaptability of the immune system to new variants, dynamics of immune memory, and contrasts success of SARS-CoV-2 vaccines with challenges faced by flu vaccines. The conversation emphasizes the importance of memory cells, neutralizing antibodies, and local tissue immunity in providing protective immunity against different variants.