Exploring T Cell Memory Responses to Vaccination and Infection

This chapter delves into the comparison of CD8 T cell memory responses following mRNA vaccination and natural infection, highlighting differences in magnitude and duration. It discusses the immune response to COVID-19 infections from nucleic acid-based vaccines, exploring vaccine efficacy in inducing T cell memory and citing specific vaccines like chat docs and AD26. The chapter also touches on the role of CD4 cells in supporting CD8 responses, antibody production, and activation of innate immune cells, underlining the importance of CD4 cells in immune functions.