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ATSRxPodcast: The Science Behind Drug Interactions: Impact of Observational vs. Causality in Interactions Affecting Acute Care Drugs

Jun 6, 2023

01:00:46

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Episode notes

Introduction

3min

How I Got to Where I Am Today

4min

The Importance of Drug Optimization in the ICU Setting

3min

The Remarkable Story of Paper Cilenteso, Back to Him and Banka Myson

3min

The Nephrotoxic Association Between Acomycin and Piptazolentase of Backtam

4min

The Role of CISTAT and C in Kidney Function

4min

Cistern C: A Biomarker for Critical Illness

4min

The Effects of Bank Plus Pit TASO on System C and Creatine

4min

The Risk of Benzodiazepine Interactions With Other Drugs

3min

10.

The Effects of Benzodiazepine on Traumatic Injury

2min

11.

The Role of Drugs in Traumatic Injury

5min

12.

The Importance of Causal Inference on Drug-Drug Interactions

2min

13.

The Ethics of Randomized Controlled Trials

3min

14.

How to Minimize Confounding by Indication in Drug Interactions

3min

15.

The Immortal Time Bias

5min

16.

How to Avoid Mortal Time Bias in an Observational Study

2min

17.

Synergistic Nephrotoxicity in Drugs

7min

This podcast features Dr. Todd Miano is a critical care pharmacist and renowned pharmacoepidemiologist who has dedicated his career to improving the safety and effectiveness of acutely ill patients. Dr. Miano has been a pioneer in research involving drug interaction effects and causality. His work has identified both interactions that may have been overhyped and ones that clinicians may not be as familiar with but should be.

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