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ATSRxPodcast: The Science Behind Drug Interactions: Impact of Observational vs. Causality in Interactions Affecting Acute Care Drugs

Breathe Easy

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The Role of CISTAT and C in Kidney Function

In 2022, you were the lead author on a paper that looked at Vekamysin together from a different perspective. You looked at a different biomarker specifically, CISTAT and C. How did your team decide to evaluate that? What is it have more clinically real impact on kidney function sort of made you go in that direction?Yeah, that's kind of what we could measure. So we had this hypothesis that the change in creatinine may not reflect actual injury. And so how do we test that hypothesis? Well, one way would be to examine the combination with an alternative biomarker.

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