Muscle Preservation with GLP-1 Drugs - Dr. Anurag Singh : 1156

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May 2, 2024

Dr. Anurag Singh, Chief Medical Officer of Timeline Nutrition and an authority on muscle biology and aging, dives into the fascinating world of GLP-1 agonists like Ozempic and Wegovy. He discusses how these drugs can aid weight loss while raising concerns about muscle preservation. Dr. Singh emphasizes the importance of maintaining muscle mass during weight loss and explores strategies for enhancing mitochondrial function. He also shares innovative testing methods and future possibilities in treatments to support long-term health and wellness.

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ADVICE

Mitigating Muscle Loss with GLP-1 Drugs

Prioritize high protein intake and strength training alongside GLP-1 drugs.
This helps maintain muscle mass, mitigating potential muscle loss from the medication.

INSIGHT

Sarcopenia and Muscle Maintenance

Tissue loss (sarcopenia) is a major pillar of aging, characterized by gradual muscle loss.
Dave Asprey maintains muscle mass by tracking it with biohacking tools and supplements like Timeline.

ANECDOTE

Fasting Experience in Sedona

Dave Asprey's first four-day fast in Sedona eliminated hunger cravings and boosted his energy.
He walked 10 miles and climbed the wrong mountain due to his increased energy levels.

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Today on The Human Upgrade, Dr. Anurag Singh, a renowned expert in muscle biology and aging, shares his expertise on the impact of GLP-1 agonists like Ozempic and Wegovy on weight loss, muscle health, and aging. In this episode, you'll learn about the science behind these popular drugs, their potential benefits, and the risks involved. Discover how you can maintain muscle mass while losing weight, enhance your mitochondrial function for better health, and what the future holds for medical treatments in weight management. Gain expert insights into making smart choices for your long-term health and wellness, whether you're considering these treatments or just curious about new health technologies.

Timestamped Highlights:

(00:00:00) Introduction to GLP-1 agonists and their popularity in weight loss.
(00:01:40) Guest introduction: Dr. Anurag Singh's expertise and background.
(00:02:50) Dr. Singh discusses the primary functions and uses of GLP-1 drugs.
(00:06:23) The significant muscle loss associated with GLP-1 drug use.
(00:10:01) Addressing common misconceptions and concerns about GLP-1 agonists.
(00:15:34) How GLP-1 agonists affect mitochondrial function and overall metabolism.
(00:20:30) Comparing the effects of fasting to GLP-1 drugs on weight loss and muscle preservation.
(00:28:43) New testing methods for mitochondrial function and their implications.
(00:35:00) Potential future directions in GLP-1 treatment and muscle preservation strategies.
(00:41:48) The concept of 'Ozempic face' and its effects on personal appearance and self-esteem.
(00:50:04) Discussion on 'Urolithin A' and its role in mitochondrial health and muscle strength.
(01:04:02) Predictions for the next innovations in weight loss and muscle health treatments.

Resources:

Vitamin Dake | www.VitaminDAKE.com
Dave Asprey’s Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books
Follow Dave on Instagram: @Dave.Asprey
Follow The Human Upgrade: @TheHumanUpgradePodcast
Want to join The Human Upgrade Podcast Live? Join Our Upgrade Collective: https://www.ourupgradecollective.com/

Sponsors:

STEMREGEN | Go to www.STEMREGEN.CO/DAVE for 20% Off
Timeline Nutrition | Go to www.TimelineNutrition.com/Dave for an exclusive discount.

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