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The Human Upgrade with Dave Asprey

Muscle Preservation with GLP-1 Drugs - Dr. Anurag Singh : 1156

May 2, 2024
Dr. Anurag Singh, Chief Medical Officer of Timeline Nutrition and an authority on muscle biology and aging, dives into the fascinating world of GLP-1 agonists like Ozempic and Wegovy. He discusses how these drugs can aid weight loss while raising concerns about muscle preservation. Dr. Singh emphasizes the importance of maintaining muscle mass during weight loss and explores strategies for enhancing mitochondrial function. He also shares innovative testing methods and future possibilities in treatments to support long-term health and wellness.
01:14:14

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Podcast summary created with Snipd AI

Quick takeaways

  • GLP-1 drugs aid in weight loss but may cause significant muscle loss, raising concerns for older individuals.
  • High-quality protein intake, exercise, and supplements can help preserve muscle mass while on GLP-1 medications.

Deep dives

Effects of GLP1 Drugs on Weight Loss and Muscle Loss

GLP1 drugs like ozempic and UgoV, initially developed for diabetes, have shown significant weight loss of about 10-15% over 12-18 months. However, there is a concern regarding muscle loss, which can amount to about 5-10 pounds or more in some cases in a year. The rapid muscle loss observed with these drugs raises concerns, especially for individuals in their 50s, 60s, or 70s.

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