The Human Upgrade: Biohacking for Longevity & Performance

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Unlocking Health Through Your Genetic Code: Healing from Veganism, Chronic Pain & Stressors - Chris Masterjohn : 1090

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Sep 21, 2023

Guest

Chris Masterjohn

In this engaging conversation, Chris Masterjohn, a PhD in Nutritional Sciences and former vegan, shares his insights on recovering from the pitfalls of veganism and the impacts of oxalates on health. He delves into the intricate connection between genetics and mitochondrial function, exploring how these factors influence energy metabolism and psychological resilience. Chris discusses personal experiences with chronic pain and anxiety management, emphasizing the importance of tailored nutritional strategies for better health outcomes. Expect humor and profound revelations throughout!

01:18:36

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ANECDOTE

Vegan Diet Negatively Impacted Health

Chris Masterjohn's mental health, teeth, and overall health significantly declined on a vegan diet.
His health dramatically improved after switching to an animal-based, Weston A. Price-style diet.

insights

INSIGHT

Rare Genes, Big Impact

Rare genes with severe effects can significantly impact health, even in heterozygous individuals.
Optimizing for these rare genes can lead to substantial health improvements.

question_answer

ANECDOTE

Riboflavin and Allergies

Chris Masterjohn eliminated his seasonal allergies within two days of supplementing with riboflavin.
This was due to a rare gene affecting his riboflavin utilization.

Get the Snipd Podcast app to discover more snips from this episode

Journeys of Health and Nutrition

02:42 • 7min

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Harnessing Genetics and AI for Personalized Health Solutions

09:55 • 4min

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The Energy Powerhouse: Mitochondria and Health Insights

13:26 • 3min

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Exploring the Genetic Role of Riboflavin in Health

16:13 • 2min

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Navigating Fertility and Mental Resilience

17:53 • 15min

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The Hidden Risks of Vegan Diets

33:09 • 20min

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Navigating Nutrient Cycles and B Vitamin Health

53:00 • 9min

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Oxalates and Mitochondrial Insights

01:01:55 • 6min

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Understanding Methylene Blue's Neurological Impact

01:07:59 • 6min

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Understanding Serotonin Syndrome and SSRIs

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The Zone Diet

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The Zone Diet, developed by Dr. Barry Sears, is a dietary plan that emphasizes a balanced intake of carbohydrates, proteins, and fats. The diet follows a specific ratio of 40% carbohydrates, 30% protein, and 30% fat, with an emphasis on low-glycemic index carbohydrates, lean proteins, and monounsaturated fats. It aims to reduce inflammation in the body, which is believed to be a key factor in weight gain, sickness, and aging. The diet encourages eating five times a day, with three meals and two snacks, and uses either the hand-eye method or Zone food blocks to measure portions. Proponents claim that following this diet can lead to rapid fat loss, improved performance, and a reduced risk of chronic diseases.

Today, we welcome back a guest from the early days of this podcast, fellow former vegan and esteemed researcher and scientist, Chris Masterjohn. Chris Masterjohn earned his PhD in Nutritional Sciences from the University of Connecticut, and has worked as a postdoctoral research associate and Assistant Professor of Health and Nutrition Sciences.

In 2016, he transitioned to entrepreneurship. These days, Chris conducts independent research, consults, develops information products, and creates free content to help people improve their health.

Chris is dedicated to sharing practical principles from complex science, and to the pursuit of truth and continuous learning. He's a biohacker from before the word “biohacking” came to be, appearing on episode 16 of this podcast when I was just getting that movement started, because he not only pays attention to how stuff works in the world and academic research, but he hacks his own body. I've always liked the way he thinks mechanistically about biology, nutrients, and what to eat.

In this conversation, we talk about how to recover from veganism and reverse the effects of oxalates, highlighting the long term health impacts of the vegan diet. His own self experimentation lately is of particular interest to me as he’s been exploring the intersection of genetics and mitochondrial health to heal niche health conditions and even quell extreme fears or stressors.

We also talk about the link between energy metabolism and psychological trauma, chronic pain and oxalate overload, and even explore the potential dangers of methylene blue from his latest 58 page research paper breaking down the importance of correct dosing.

If you’re a true biohacker, you’re going to love this deep dive into how minerals and metabolism play a huge role in our biology.

(03:47) Genetic Optimization: A New Approach to Healing Chronic Pain & Disease

• How his perspective on nutrition has changed since our first episode

• The extreme effects veganism had on his health

• Using genetics research to find solutions to rare health issues

• The role of AI in diagnosing health conditions—now and in the future

• Focusing on mitochondria as the root cause to heal health issues

• Access his program: chrismasterjohnphd.com

• What will reverse the anti fertility trend?

• The psychological rewiring required to heal chronic disease states

• Lowering your stress response with GABA and hierarchical exposure therapy

• How energy metabolism and psychological trauma symptoms are related