Tetragrammaton with Rick Rubin Andrew Huberman, Ph.D. (Part 2)
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Sep 19, 2025 
Dr. Andrew Huberman, a tenured neuroscientist at Stanford, returns to delve deeper into fascinating neuroscience topics. He discusses the therapeutic potential of MDMA for PTSD and the contrasting effects of ketamine and psilocybin. Huberman also shares daily tools for health, including Yoga Nidra and the impacts of caffeine and nicotine. He reflects on technology's role in advancing brain research and the transformative power of spiritual practices like prayer. Plus, insights into effective teaching and his experience writing a new book add depth to their conversation.
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MDMA Trial Changed His Emotional Processing
- Andrew Huberman described participating in an MDMA clinical trial that helped him forgive others and himself.
- He said the experience lifted emotionally heavy things and changed him for the better.
Structure Sessions With Guide, Eye Mask, Integration
- Use an experienced guide and eye mask during MDMA or psychedelic sessions to avoid distraction and focus on therapeutic content.
- Include preparatory discussion sessions and post-session integration to capitalize on the experience.
Plasticity Is The Therapeutic Engine
- Psychedelics and empathogens enhance neuromodulators to open windows of plasticity lasting weeks.
- The acute experience is a catalyst; lasting change depends on how you use the post-session plasticity.
