The Peter Attia Drive

#38 - Francisco Gonzalez-Lima, Ph.D.: Advancing Alzheimer’s disease treatment and prevention – is AD actually a vascular and metabolic disease?

Jan 28, 2019
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1
Introduction
00:00 • 6min
2
The Importance of Functional Brain Mapping
05:40 • 2min
3
The Importance of Functional Studies in the Brain
07:11 • 2min
4
The Unique Look of the Brain
09:33 • 2min
5
The Different Types of Engineering
11:07 • 2min
6
The Evolution of the Brain
12:46 • 3min
7
The Redundancy of the Brain in Other Organisms
15:42 • 2min
8
The Role of the Midbrain in Behavior
17:24 • 3min
9
The Role of the Cerebral Cortex in Reflexes
20:06 • 2min
10
The Role of the Cortical Regions in the Brain
21:42 • 2min
11
The Failure of Alzheimer's Disease Research
23:17 • 2min
12
The Origins of Alzheimer's Disease
25:03 • 4min
13
The PSCN1 or 2 Mutation in Alzheimer's Disease
29:31 • 2min
14
The False Premise of Alzheimer's
31:09 • 2min
15
The Role of Amyloid Beta Deposition in Alzheimer's Disease
33:15 • 2min
16
The Role of Amyloid Beta in Alzheimer's Disease
35:15 • 2min
17
The Role of Amyloid Beta in Alzheimer's Disease
37:32 • 3min
18
The Role of Hypometallism in Alzheimer's
40:17 • 4min
19
The Role of the Hippocampus in Memory Formation
44:23 • 2min
20
The Different Types of Memory Diseases in Alzheimer's Disease
46:28 • 2min
21
The Effects of Aging on Memory
48:30 • 2min
22
How to Distinguish Between Mild Cognitive Impairment and the Harbinger of Something Pathologic
50:50 • 3min
23
The Role of the Vascular System in Alzheimer's Disease
54:11 • 3min
24
The Role of Vascular Biology in Cognitive Function
57:05 • 2min
25
The Nonlinear Relationship Between Perfusion and Perfusion
58:40 • 2min
26
The Effects of High Blood Pressure on Microvascular Disease
01:00:28 • 2min
27
The Effects of Vascular Hyper-Profusion on the Brain
01:02:23 • 4min
28
The Different Types of Chronic Hypo-Perfusion
01:05:58 • 2min
29
The Epidemiology of Alzheimer's Disease
01:08:11 • 2min
30
The Importance of the Electron Transport Chain
01:10:08 • 2min
31
The NADH and the Electron Transport System in the Mitochondria
01:12:00 • 4min
32
The Importance of Eating Carbohydrates
01:16:19 • 2min
33
The Effects of Chronic Hyper-Profusion on Mitochondria
01:18:27 • 3min
34
The Importance of Complex Four in Ischemia
01:21:05 • 2min
35
The Effects of Cyanide on Oxygen Utilization
01:23:20 • 2min
36
Cyanide and Alzheimer's
01:25:00 • 2min
37
The Effects of Amyloid Beta on Cognitive Impairment
01:26:46 • 2min
38
The Role of Cytochrome C in Brain Damage
01:29:13 • 5min
39
The Role of Mitophagy in Alzheimer's Disease
01:33:55 • 2min
40
The Role of Hypoxia in Brain Injury
01:35:41 • 2min
41
Cytochrome C Oxidase and Alzheimer's Disease
01:37:25 • 2min
42
The History of Madeline Blue
01:39:51 • 5min
43
The Effects of Madeline Blue on Methemoglobinemia
01:44:23 • 4min
44
The History of Metalin Blue
01:47:58 • 3min
45
The History of Metalin Blue
01:50:42 • 3min
46
The Impossible Situation in Metalin Blue
01:53:38 • 2min
47
The Pros and Cons of the Methylene Blue Derivative
01:55:37 • 2min
48
Methylene Blue: An Anti-Towel Medication
01:57:53 • 2min
49
The Effects of Methylene Blue on Towel Aggregation
01:59:35 • 3min
50
The FDA Approved Mementine for Early Alzheimer's Disease
02:02:22 • 3min
51
The Role of Near-Infrared Light in Mitochondrial Reaction
02:04:52 • 2min
52
The Effects of Methylene Blue on Mitochondrial Function
02:07:04 • 3min
53
Metal and Blue: A Synergistic Approach to Neuroscience
02:10:08 • 2min
54
The Role of Photodynamic Therapy in the Treatment of Malaria
02:11:54 • 2min
55
The Benefits of Ketogenic Diet in Preventing Cardiovascular Disease
02:13:36 • 1min
56
The Effects of Ketones on the Brain
02:15:03 • 2min
57
The Effect of Ketogenic Diet on Mitochondria
02:16:42 • 2min
58
The Alternative to the Bulletproof Coffee
02:18:21 • 2min
59
The Role of Fasting in Obesity
02:20:24 • 5min
60
The Benefits of Methylene Blue for Traumatic Brain Injury
02:25:24 • 3min
61
The Pros and Cons of Metylene Blue
02:28:29 • 2min
62
The Longevity Science Podcast
02:30:13 • 2min