AI-powered
podcast player
Listen to all your favourite podcasts with AI-powered features
Sigma Nutrition Radio
#495: Circadian Clocks in Muscle & Exercise as a Time Cue – Prof. Karyn Esser
Sep 12, 2023
35:27
AI Summary
Highlights
AI Chapters
Episode notes
Podcast summary created with Snipd AI
Quick takeaways
- Exercise can shift the phase of muscle clocks and regulate gene expression, highlighting the intrinsic capacity of muscle cells to respond to exercise-related cues and suggesting the role of clock mechanisms in exercise adaptations.
- Circadian phase differences in muscle strength and mitochondrial function indicate the potential trainability and adaptability of muscle clocks through exercise, emphasizing the importance of considering circadian factors in training schedules for optimal performance.
Deep dives
Exercise and Circadian Rhythms in Muscle
Exercise has a significant impact on circadian rhythms in skeletal muscle. Studies have shown that exercise can shift the phase of the muscle clocks and regulate gene expression. An experiment with mice exercising during their normal sleep phase demonstrated a significant shift in the muscle clocks, closer to the time of exercise. Another study using acute bouts of exercise at different times of day showed that exercise can induce phase advances or delays in the muscle clocks. Furthermore, muscle cells grown in vitro also exhibited the ability to sense contractions and adjust their clock phase accordingly. This highlights the intrinsic capacity of muscle cells to respond to exercise-related cues and suggests that the clock mechanisms play a role in exercise adaptations in muscle.
Get the Snipd
podcast app
Unlock the knowledge in podcasts with the podcast player of the future.
AI-powered
Discover
highlights
Listen to the best highlights from the podcasts you love and dive into the full episode
Save any
moment
Hear something you like? Tap your headphones to save it with AI-generated key takeaways
Share
& Export
Send highlights to Twitter, WhatsApp or export them to Notion, Readwise & more
AI-powered
podcast player
Listen to all your favourite podcasts with AI-powered features
Discover
highlights
Listen to the best highlights from the podcasts you love and dive into the full episode