SmartLess "David Sinclair"
5 snips
Feb 22, 2021 
David Sinclair, an award-winning biologist and professor of genetics, shares his groundbreaking work in aging and anti-aging. He discusses the power of fasting, exercise, and diet to enhance longevity. Humor blends with science as he reveals how he reversed the age of a mouse’s eye. The conversation also touches on CRISPR and its potential to tackle genetic disorders. Sinclair highlights the societal impacts of increased life span and the ethics surrounding it, offering listeners a thought-provoking yet entertaining outlook on the future of health.
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Lifestyle Recommendations
- Eat less often and exercise regularly, getting your heart rate up.
- Prioritize a plant-based Mediterranean diet, but occasional burgers are fine.
Hormesis and Longevity
- Restricting protein intake, like with plant-based diets, activates longevity genes.
- This hormesis effect puts the body in a defensive mode, boosting health.
Will Arnett's Longevity Genes
- Will Arnett boasts of family longevity, with relatives living to 95 and beyond.
- He jokingly claims he'll live to 130 due to good genes.
