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The Stronger By Science Podcast

Q&A: Insulin resistance and hypertrophy, stimulant metabolism, and BMR variability

Feb 7, 2024
The podcast discusses topics such as researching new subjects, diabetes and hypertrophy, the effect of a pump on movements, too much isolation work, and the future of the podcast. They also cover muscle size and leverage, the impact of nicotine and caffeine on clearance rates, BMR variability, and incorporating plyometrics and explosive training for basketball athletes.
02:21:53

Podcast summary created with Snipd AI

Quick takeaways

  • Type 2 diabetes may have a small negative impact on muscle growth, but it does not make it impossible to build muscle.
  • The moment arm (lever) created by muscles can improve when they get bigger, resulting in more advantageous movements.

Deep dives

Impact of Insulin Resistance and Diabetes on Hypertrophy

Research suggests that type 2 diabetes may have a small negative impact on muscle growth, but it does not make it impossible to build muscle. Studies on diabetics show a moderate increase in lean body mass, indicating that muscle growth is still possible. The reduction in muscle growth is estimated to be around 50% compared to non-diabetics, but this difference may be influenced by factors such as age and training intensity. Metformin, a common medication for type 2 diabetes, may have a slight negative impact on hypertrophy, but more research is needed to fully understand its effects. Overall, the research does not support the claim that insulin resistance or diabetes completely hinders muscle growth.

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