

EB. 136: High-Carb Diets Cause Insulin Resistance, Overeating, and Glycation? (Eric Westman Debate Follow-Up Part 2)
Sep 16, 2025
Explore the complexities of low-carb diets, including how low T3 and high glucagon levels impact health. Discover why the brain prefers glucose over fat and the debates surrounding metabolic rates and longevity. Uncover the relationship between high-carb diets and insulin sensitivity, as well as the misconceptions about glycation. Additionally, learn why some studies suggest high-carbohydrate diets could reduce cravings and promote healthier eating habits. It's a deep dive into dietary myths and metabolic insights!
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Keto→High-Carb Study Is Confounded
- The Cooper study flipped keto-adapted women to high-carb ad lib and saw weight gain and some inflammatory markers rise.
- Lack of diet control and weight gain confound attributing those marker changes directly to carbs.
Assess Symptoms Alongside Labs
- Monitor symptoms, not just lab numbers, when evaluating low T3 or hormonal shifts on low-carb diets.
- Watch for low body temperature, hair loss, mood, libido, and digestive slowing as early signs.
Lab Shifts Can Predict Future Decline
- Low T3, low testosterone, and high glucagon on low-carb diets can be clinically subtle but meaningful.
- Jay warns lab shifts often precede symptomatic decline and have known downstream harms.