Discover why popular beliefs about lipolysis and fat loss may be misguided. Learn how less lipolysis can actually lead to more effective fat loss. The podcast dives into the impacts of fat release on conditions like diabetes and fatty liver disease. It also emphasizes focusing on holistic strategies rather than just boosting fat burning. This enlightening discussion challenges the conventional wisdom surrounding dieting and exercise for weight management.

In this conversation, Jack, co-creator of Analyze & Optimize, shares insights into Ray Peat's dietary principles and critiques Robert Lustig's claims about fructose being as harmful as alcohol. The discussion also touches on the complex role of serotonin, challenging its portrayal as simply a 'happy hormone,' and dives into the potential negative impacts of the carnivore diet on gut health. Additionally, they explore the health risks associated with hormonal contraceptives and reflect on Dave Asprey's views regarding dietary choices.

The podcast dives into why high-carb diets can increase triglycerides and whether you should be concerned. It explores the role of small, dense LDL particles in heart disease and compares lipid values between different dietary approaches. There's a discussion on low HDL levels and their impact on heart health, as well as the relationship between high triglyceride levels and cardiovascular risk. The insights provided help clarify metabolic health and the complexities surrounding lipid panels.

The podcast dives deep into the controversy surrounding seed oils and their health implications, challenging the simplistic 'calories only' view of nutrition. It critiques the unrealistic body image promoted by fitness influencers and discusses the health risks associated with steroids. The hosts also tackle misunderstandings related to omega-3s and their sources, highlighting the nuances of dietary fats. Furthermore, they examine the complexities of insulin resistance and the influence of polyunsaturated fats on chronic diseases, emphasizing the need for a holistic view of nutrition.

Explore the surprising roles of estrogen beyond reproduction, including its impact on digestion and muscle growth. Discover whether testosterone can convert to estrogen and how hormonal imbalances can lead to health issues like weight gain and cancer risk. Learn about the effectiveness of calcium D-glucarate for estrogen detoxification and the importance of personalized wellness strategies. This discussion sheds light on common misconceptions and advocates for informed dietary choices to maintain hormonal balance.

Georgi Dinkov, an expert in bioenergetics and cellular metabolism, addresses criticism regarding estrogen's links to cancer and weight gain. He delves into the often misunderstood roles of serotonin, challenging traditional views on its connection to depression. The discussion also critiques common beliefs about thyroid issues on a carnivore diet and the health implications of orange juice, questioning popular dietary recommendations. Dinkov shares insights on the complexities of hormone therapy and the nutritional intricacies of modern diets.

Explore a revolutionary take on fat loss that challenges the traditional calories in, calories out model. Discover how the body's mitochondrial function plays a crucial role in determining whether food is stored as fat or used for energy. Learn why simply eating less and exercising more often leads to cycles of weight gain and hunger. Gain insights into how you can actually lose fat while eating more and the impact of energy availability on stress hormones and hunger.

Free Energy Balance Food Guide: https://jayfeldmanwellness.com/guide   The Nutrition Blueprint: https://mikefave.com/the-nutrition-blueprint/   Danny's Telegram: https://t.me/dannyroddy   Danny's Substack: https://dannyroddy.substack.com/   Timestamps: 0:00 – intro 0:36 – catching up: fruit quality in the Philippines and Ecuador, and the effects of mold toxicity 5:28 – Kiran Krishnan and Nutrition with Judy discuss why they believe coconut oil should not be consumed 9:55 – whether coconut oil causes greater release and absorption of endotoxin (LPS) 12:11 – should you eat coconut oil even if your ancestors didn't? 21:08 – how MCT oil compares to coconut oil as it relates to the microbiome 32:28 – concerns with adopting dietary ideologies 36:21 – Morley Robbins on why the thyroid doesn’t run the body and we shouldn’t ignore the adrenals 47:05 – adrenal fatigue as a systemic issue and whether the thyroid or adrenals run the body 56:45 – our take on Real Food Gangsta’s (Josh & Jeanne Rubin) view that the adrenal glands regulate the body’s mineral and fuel availability 1:07:02 – the importance of optimal gut motility and how to alleviate gut motility issues such as constipation and loose stools 1:19:54 – which lab tests provide the most valuable information 1:25:14 – the benefits of spending time without stimulation (letting your mind wander) during the day 1:27:20 – simple mindset strategies to help you reach your goals 1:32:55 – Alan Aragon’s argument that not all seed oils are harmful 1:40:56 – why the claim that seed oils lower cholesterol does not mean they are healthy 1:42:25 – whether animal studies are valuable for understanding the effects of seed oils on human health

In this episode we discuss: Whether “calories in, calories out” is physiologically accurate The many misconceptions related to “calories in, calories out” Why a calorie deficit is NOT required for fat loss Why “calories in, calories out” does not mean that eating less and exercising more is good advice for fat loss What most people miss when it comes to “calories in, calories out”   Free Energy Balance Food Guide: https://jayfeldmanwellness.com/guide   Free Energy Balance Mini-Course: https://www.jayfeldmanwellness.com/energy/   Check out the Energy Balance Solution program here: https://www.jayfeldmanwellness.com/solution/     Click here to check out the show notes: https://www.jayfeldmanwellness.com/ep-123-debunking-the-cico-myth-calorie-deficits-are-not-required-for-fat-loss/   Timestamps: 0:00 – intro 1:07 – questions about the calories-in, calories-out (CICO) model of weight loss that I’ll be answering  7:18 – what is (and isn’t) a calorie?  11:49 – misapplications of CICO and why CICO is not physiologically accurate in the ways most people use it  19:46 – why the idea that “a calorie is a calorie” is misleading  29:11 – how energy in food is measured and the inaccuracy of food labels  36:16 – the impact of behavioral compensation and metabolic adaptation on energy expenditure  42:07 – how cutting calories lowers metabolism, reduces thyroid function, and increases stress hormones, appetite, and weight regain  48:26 – Herman Pontzer’s Constrained Model of Energy Expenditure and the adverse effects of energy deficits  52:21 – whether CICO can accurately represent physiology  1:00:04 – a simplified version of CICO  1:05:41 –why calories do not equal usable energy or weight  1:13:27 – examples demonstrating the issues with common CICO misconceptions  1:21:09 – summarizing the central issues with CICO and how you can lose body fat without a caloric deficit  1:28:13 – whether there’s value to CICO

Bryan Johnson, a trailblazer in longevity and wellness, shares insights on his Longevity Blueprint. He discusses the pitfalls of extreme biohacking and the real cost of caloric deficits. The conversation delves into the complexities of diet, stressing the importance of individual responses over popular health trends. Stress and its impact on metabolic health are explored, alongside a critical look at glucagon and insulin’s roles. Johnson highlights the need for a balanced approach in health management and resilience building.