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Differentiating UC and Crohn's Disease
- Differentiating ulcerative colitis (UC) from Crohn's disease (CD) is challenging but crucial for management.
- Bloody stools and tenesmus favor UC; skip lesions, fistulas, and malnutrition point to CD.
Assess Extraintestinal Manifestations
- Always assess for extraintestinal manifestations like arthritis and uveitis in IBD patients.
- Screen for primary sclerosing cholangitis (PSC) in UC given its associated cancer risks.
Endoscopic Differences: UC vs Crohn's
- UC usually shows continuous, circumferential inflammation beginning in the rectum.
- Crohn's shows skip lesions, cobblestoning, and can affect any GI tract part, including terminal ileum.