Muscle, Menopause & GLP-1s: How to Protect Your Strength While Losing Fat | Dr Jack Mosley

Jul 25, 2025

Dr. Jack Mosley, a GP registrar and author of "Food Noise," dives into the complexities of food cravings and the powerful role of GLP-1 medications like Ozempic. He discusses how 'food noise' is shaped by genetics and emotions, leading to cravings that can derail nutrition efforts. The conversation highlights the importance of combining GLP-1s with healthy lifestyle changes, including regular exercise and resistance training, especially during menopause. He also addresses the risks of rapid weight loss on muscle preservation and overall health.

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INSIGHT

Why Food Noise Varies

Genetic predispositions and environmental factors heavily influence why some people experience more food cravings or "food noise."
Processed foods are designed to overwhelm our reward centers and amplify cravings, especially under stress or fatigue.

INSIGHT

Overfed but Undernourished

Many people are overfed yet undernourished, causing cravings driven by nutrient deficiencies.
Processed foods trick the body by mimicking nutrient signals without providing real nutrients, worsening cravings.

INSIGHT

How GLP-1 Medications Work

GLP-1 medications, like Ozempic, work on the pancreas, gut, and brain to regulate blood sugar, slow gastric emptying, and reduce appetite and cravings.
Their brain effects specifically quiet food cravings or "food noise," making them highly effective for weight loss.

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Angela examines the complexities of food noise and the impact of GLP-1 medications with Dr. Jack Mosley, author of "Food Noise." They explore why some individuals experience more food cravings than others, discussing the interplay of genetic and environmental factors, as well as the emotional components tied to eating.

KEY TAKEAWAYS

Food Noise and Cravings: Individuals experience varying levels of "food noise," or cravings, influenced by genetic predispositions and environmental factors
Nutritional Deficiencies: Many people are overfed but undernourished, leading to cravings driven by nutrient insufficiencies
GLP-1 Medications: GLP-1 medications, such as Ozempic and Wegovy, work by regulating blood sugar, slowing gastric emptying, and affecting brain pathways
Importance of Lifestyle Changes: While GLP-1 medications can aid in weight loss, they should be accompanied by lifestyle changes, including a nutritious diet and regular exercise

TIMESTAMPS AND KEY TOPICS

[00:05:25] GLP-1 and appetite reduction.

[00:09:14] Rapid weight loss and muscle loss.

[00:20:06] Importance of muscle in aging.

[00:36:09] Scurvy and modern nutrition.

[00:41:54] Weight loss medications and recipes.

VALUABLE RESOURCES

Get a free snapshot of your health and personalised report at www.yourtotalhealthcheck.com

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Sign Up to Angela’s Weekly Fresh Starts Email to transform your health, energy, and longevity with just ONE small habit every week - angelafoster.me/freshstart

Food Noise: How weight loss medications & smart nutrition can silence your cravings https://amzn.eu/d/82fCVHP

Intermittent Fasting, Intelligent Exercise & Simple Habits to Boost Longevity & Performance with Dr Michael Mosley https://lnk.to/EP_202

ABOUT THE GUEST

Jack studied medicine at Newcastle University and received a Distinction in his Masters of Research in diabetes with Professor Roy Taylor, whose remarkable work proved the transformative effect of weight loss and diet on type 2 diabetes, leading many hundreds of thousand putting their diabetes into remission

ABOUT THE HOST

Angela Foster is an award winning Nutritionist, Health & Performance Coach, Speaker and Host of the High Performance Health podcast. A former Corporate lawyer turned industry leader in biohacking and health optimisation for women, Angela has been featured in various media including Huff Post, Runners world, The Health Optimisation Summit, BrainTap, The Women’s Biohacking Conference, Livestrong & Natural Health Magazine.

Angela is the creator of BioSyncing®️ a blueprint for ambitious entrepreneurial women to biohack their health so they can 10X how they show up in their business and their family without burning out. Angela’s BioSyncing®️ Blueprint is currently closed. Click here to get on the waitlist.

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