
LONGEVITY with Nathalie Niddam #399: Longevity Rewired: Hormones, Sunlight & The Weight Loss LIE | Reversing Aging in 2025 With Nat Niddam
Dec 26, 2025
In this insightful discussion, health and metabolic coach Ben Azadi debunks the calorie-focused approach to weight loss, highlighting the impact of hormones and gut microbiome. Research scientist Ian White reveals how young blood factors can rejuvenate aging tissues. Dr. Robert Lufkin critiques conventional chronic disease treatments, advocating for lifestyle strategies. Dr. Jenn Simmons addresses the risks of overdiagnosis in breast cancer screening and promotes smarter alternatives, emphasizing the importance of tailored care and hormone therapy.
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Weight Is A Symptom, Not The Root
- Weight is a symptom, not the root problem of health decline.
- Ben Azadi says hormones and cellular inflammation drive weight more than calories alone.
Gut Microbiome Can Override Calories
- Gut microbiome composition can drive weight change independent of calorie intake.
- Ben Azadi cites a fecal transplant study where obese participants lost weight without dietary change.
Build A Flexible Metabolism
- Aim for a healthy, flexible metabolism rather than 'fast' or 'slow' labels.
- Ben Azadi recommends rebuilding metabolic resilience instead of extreme deficits.


