The Doctor's Kitchen Podcast #333 Why Muscle Is the Organ of Longevity with Dr Gabrielle Lyon
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Jan 28, 2026 
Dr Gabrielle Lyon, physician and founder of the muscle-centric medicine movement and author of Forever Strong, reframes muscle as a metabolic and endocrine organ. She covers why muscle drives metabolic health and longevity. Practical protein targets and how to dose protein per meal. Training principles for strength, metabolic flexibility, recovery habits, and building lasting standards for family health.
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Muscle As The Metabolic Hub
- Muscle is the largest organ system and acts as a metabolic and endocrine hub that drives longevity and resilience.
- Gabrielle Lyon argues muscle health, not obesity alone, underpins metabolic control and disease risk.
What Healthy Metabolism Looks Like
- Metabolism is the sum of chemical reactions; healthy muscle should burn fatty acids at rest rather than glucose.
- Overconsuming carbohydrates forces muscle to burn carbs at rest and distorts metabolism.
Daily Protein Targets And Meal Dosing
- Aim for 0.7–1.0 grams per pound (≈1.5–2.2 g/kg) of target body weight, and don't go below ~100 g/day total protein.
- Dose protein per meal (35–55 g) to trigger muscle protein synthesis and support muscle health.
