

#215 - The gut-brain connection | Michael Gershon, M.D.
119 snips Jul 25, 2022
Michael Gershon, a renowned Professor at Columbia University, dives deep into the fascinating world of the gut-brain connection. He reveals how the gut communicates with the brain and vice versa, underscoring the unique roles of serotonin in digestion. Topics include the effect of diet on satiety signaling, the impact of antidepressants on gut health, and the complexities of gut microbiome testing. Gershon also discusses 'leaky gut' and the importance of probiotics, offering insights into how our dietary choices influence our overall health.
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The GI System: A Tube
- The gastrointestinal (GI) system is a tube from mouth to anus, essentially internalized external space.
- The inside of the gut is outside the body and requires protection while absorbing nutrients.
Gut Development
- The GI system develops from a flat disc that folds during embryogenesis.
- The gut matures during the fetal period and becomes functional by birth.
Gut Blood Supply and Portal System
- The gut's blood supply is unique with a portal system connecting it to the liver.
- The liver processes absorbed nutrients before they enter systemic circulation.