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#215 - The gut-brain connection | Michael Gershon, M.D.

The Peter Attia Drive

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Gut-Brain Connection: Serotonin, Autism, and Microbiome Dynamics

This chapter explores the intricate interplay between serotonin transport mechanisms and autism spectrum disorder, using a genetically modified mouse model to highlight relevant behavioral traits and gastrointestinal defects. It discusses the complex ecosystem of gut bacteria, their influence on health, and the impact of in utero exposure to SSRIs. Additionally, the chapter addresses the significant role of gut microbiota in obesity and the challenges surrounding fecal transplants as a potential treatment for issues like C. diff infections.

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