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#215 - The gut-brain connection | Michael Gershon, M.D.

The Peter Attia Drive

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The Gut-Brain Connection: A Historical Perspective

This chapter explores the intricate relationship between the gut and the nervous system, focusing on the gut's autonomous nervous system known as the 'second brain.' It highlights key historical discoveries, particularly during the Civil War and early 20th century, that shaped our understanding of gut function and its independence from the central nervous system. The chapter also discusses gut anatomy, cell roles, and the significant implications for health, particularly regarding cancer susceptibility and nutrient absorption.

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