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Age Less / Live More

587: The Truth About Aging with Stephen Kritchevsky

Sep 27, 2023
Dr. Stephen Kritchevsky joins this week's podcast to help us separate the signal from the noise of longevity practices. Topics include aging research using animal models, the effects of caloric restriction on aging, complexity of diet and health impacts, role of dietary patterns in muscle health, and tips for improving hip mobility.
41:38

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Quick takeaways

  • Animal models provide valuable insights into anti-aging interventions and the underlying mechanisms of aging.
  • Improving health span is essential, as extending lifespan without maintaining good health can lead to increased disability.

Deep dives

The Promise and Dangers of Longevity Interventions

Long Jevity is gaining popularity, with tech millionaires investing in various unconventional treatments for anti-aging. While some of these interventions may be useless, others could potentially be harmful. However, there is ongoing research on interventions that could slow down the aging process and improve health span. Animal models have identified pathways that, when manipulated, can extend lifespan. Some interventions being studied include caloric restriction and the use of compounds like rapamycin and metformin. However, caution is needed as unscrupulous individuals are taking advantage of the excitement around the field, making false claims about anti-aging treatments.

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