The Internet Book of Critical Care Podcast

IBCC Episode 127 - Spontaneous Bacterial Peritonitis (SBP)

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Apr 28, 2023
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ADVICE

Tap All Cirrhotic Patients with Ascites

  • Always tap cirrhotic patients with ascites upon hospital admission, even if they seem stable.
  • This helps identify SBP early, which can be a silent driver of multi-organ failure.
INSIGHT

Absolute Neutrophil Count in SBP

  • In ascites fluid analysis, the absolute neutrophil count (ANC), not the total cell count, is key for diagnosing peritonitis.
  • An ANC over 250 indicates peritonitis, often SBP, requiring prompt treatment.
ADVICE

Differentiating SBP from Secondary Peritonitis

  • Differentiating between primary (SBP) and secondary bacterial peritonitis is crucial, as treatment differs significantly.
  • Look for red flags like overt peritonitis, complex ascites fluid, multiple organisms on culture, or lack of response to antibiotics.
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