

BS 201 Brain Development with Bill Harris
Oct 28, 2022
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Origin of Interest
- Bill Harris's interest in developmental neurobiology sparked during his graduate studies on fruit flies.
- He observed a colorblind fly where a color-sensitive cell transformed into a different type, raising developmental questions.
Ancient Neural Mechanisms
- Even single-celled organisms like Paramecia exhibit basic neural mechanisms, like action potentials using calcium ions.
- Many components of neural activity, including neurotransmitters, evolved before nervous systems.
Tripartite Brain Structure
- Vertebrate nervous systems share a common structural organization (forebrain, midbrain, hindbrain).
- This tripartite brain structure dates back to ancestors of both vertebrates and invertebrates like flies.