Brain Science with Ginger Campbell, MD: Neuroscience for Everyone cover image

BS 201 Brain Development with Bill Harris

Brain Science with Ginger Campbell, MD: Neuroscience for Everyone

CHAPTER

The Hox Gene Is a Transcription Factor

You told us that the Hox gene is a transcription factor. It's not a morphogen. Would you tell us again what a morphogen does? That's the thing that makes the gradient? Let's give an example of a morphogen: Retinoeic acid, which can leak out of a cell and diffuse through the cellular environment. If you're making a lot of retinoeic Acid at one place and destroying a lot of it at another place, then you have a gradient ofretinoeic acids percolating around the cells.

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