The Energy Balance Podcast

EB. 34: Macros for Insulin Resistance & Diabetes and Melatonin & GABA for Sleep (Q & A)

Nov 23, 2020
Discover how to tailor macronutrient ratios to combat insulin resistance and diabetes. Learn about the often-overlooked factors influencing insulin sensitivity beyond just diet. Uncover the drawbacks of melatonin supplements and explore whether GABA can enhance sleep. Find out why reconsidering melatonin might improve your rest and discover alternative methods to promote healthy sleep. This engaging conversation provides practical insights on nutrition and sleep optimization for better health.
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INSIGHT

Endotoxin and Insulin Resistance

  • Endotoxemia, a chronic low-grade inflammation from bacterial cell walls, seems to be a primary factor in type 2 diabetes and insulin resistance.
  • Elevated blood lipids can bind endotoxin, but also contribute to insulin resistance via circulating free fatty acids.
ADVICE

Dietary Strategies for Insulin Resistance

  • Include moderate saturated and monounsaturated fats from sources like butter, beef tallow, and cocoa butter to protect against endotoxin and stimulate bile release.
  • Consume easily digestible carbohydrates with plant compounds, especially from whole fruits and 100% fruit juice, to support gut health.
ANECDOTE

Anecdotal Dietary Successes

  • Fruitarian, vegetarian, keto, and carnivore diets have shown anecdotal success in managing insulin resistance and diabetes.
  • These successes may stem from eliminating problematic foods, increasing nutrient intake, and modulating gut bacteria.
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