
Vital Signs with Jacob Effron and Nikhil Krishnan
On Vital Signs, Jacob Effron and Nikhil Krishnan dig into cutting-edge trends in healthtech and the people shaping them. Every two weeks they’ll explore a new sub-sector and trend with policy leaders, startup founders and industry executives.
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Latest episodes

Mar 28, 2023 • 38min
Ep 19: Mike Kopko on ACO Reach and The Future of Health Exchanges
Jacob and Nikhil sit down with Mike Kopko, CEO and co-founder of Pearl Health to discuss Pearl’s care model and what it’s been like building the company as ACO Reach evolved. Mike also shares some great stories negotiating claims in the early days of Oscar.

11 snips
Mar 16, 2023 • 39min
Ep 18: Dr. Jeffrey Kang on CVS/Walgreens' Role in Healthcare and The Future of Risk Adjustment and Senior Care
Jacob and Nikhil sit down with Dr. Jeffrey Kang, CEO of WellBe Senior Medical, and former President of ChenMed, SVP Health and Wellness Solutions at Walgreens, CMO at Cigna, CMO at CMS and CEO of Urban Medical Group. They discuss risk adjustment, retailers in healthcare and how healthcare has/hasn't changed since his work doing risk-based care for complex patients and at CMS in the 80s and 90s.

Mar 1, 2023 • 49min
Ep 17: Naomi Allen on How to Sell to Employers and the Future of Mental Healthcare
Jacob and Nikhil sit down with Naomi Allen, CEO and founder of Brightline (child and teen focused mental health company that’s raised >$100M) and Castlight/Livongo exec. They discuss the difficulties of balancing employer customers and employee satisfaction at Castlight, how Livongo captured member delight and Brightline's care model.

Feb 14, 2023 • 39min
Ep 16: Dr. Jaewon Ryu on Geisinger's Fresh Food and DNA Sequencing Programs and the Future of Clinician Training
Jacob sits down with Geisinger CEO Dr. Jaewon Ryu to discuss how he and Geisinger think about their Fresh Food Farmacy, population-wide DNA sequencing efforts, and transforming medical education.

Feb 2, 2023 • 27min
Ep 15: Dr. Jenny Schneider on What Livongo Got Right and Improving Rural Healthcare
Jacob sits down with Homeward Health CEO and former Castlight and Livongo CMO Dr. Jenny Schneider to discuss solving provider shortages in rural markets, how tech can/can’t help care and what Livongo did to make coaching more effective.

6 snips
Jan 19, 2023 • 41min
Ep 14: Vijay Kedar on Oscar Reflections and What's Required to Make At Home Care Work
Jacob and Nikhil sit down with Tomorrow Health CEO and former Oscar Texas GM Vijay Kedar to discuss lessons he learned at Oscar, reflections on the ACA market, the nuances of operationalizing at home care and what Tomorrow is building.

Jan 5, 2023 • 37min
Ep. 13: Annual Predictions and Robin Shah and Dr. Bobby Green on Designing New Cancer Care Models and The Future of Oncology
Jacob and Nikhil discuss annual health-tech predictions and are then joined by Thyme Care co-founders Robin Shah and Dr. Bobby Green to discuss the nuances of taking risk in oncology, lessons on selling to providers, and what they're building at Thyme Care.
0:00-9:10 Jacob & Nikhil discussion
9:13-end Thyme Care founders interview with Robin Shah and Dr. Bobby Green

Dec 14, 2022 • 39min
Ep 12: Chris Gibson on Building a Platform Biotech and The Future of R&D
Jacob sits down with Chris Gibson, the co-founder and CEO of Recursion, to discuss how Recursion predicted drugs that would be effective for COVID, his take on different techbio business models, what pharma R&D will look like in 25 years and more.

Nov 29, 2022 • 41min
Ep 11: Dr. Arif Nathoo on the Evolution and Future of Healthcare Data and Building a Vertical SaaS Platform
Jacob sits down with Dr. Arif Nathoo, the CEO of Komodo Health (most recently valued at $3.3B) to discuss Komodo’s journey from a single app to a platform, why EHR data is overhyped and where healthcare data is headed.

Nov 16, 2022 • 49min
Ep 10: Dr. Bob Kocher on the Future of Health Systems and Increasing Healthcare Productivity
Jacob and Nikhil sat down with Dr. Bob Kocher, the Venrock partner who helped write the Affordable Care Act while in the Obama administration to discuss how health systems will increase productivity, what drives healthcare costs, and his reflections on the ACA.