
Vital Signs with Jacob Effron and Nikhil Krishnan
On Vital Signs, Jacob Effron and Nikhil Krishnan dig into cutting-edge trends in healthtech and the people shaping them. Every two weeks they’ll explore a new sub-sector and trend with policy leaders, startup founders and industry executives.
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Latest episodes

Sep 27, 2022 • 35min
Ep 7: Seema Verma on Running CMS During COVID and Drug Pricing
Jacob sits down with Seema Verma to talk about rapid policymaking during COVID, recent drug pricing legislation, her reflections on her time at CMS and what areas of tech she's most excited about.

4 snips
Sep 13, 2022 • 45min
Ep 6: Nikhil Krishnan on Doctor Influencers and Healthcare Hot Takes
Nikhil Krishnan, founder of Out of Pocket and healthcare meme king, discusses his journey, teaching healthcare business, doctor influencers, trust in the healthcare system, AI in healthcare, company preferences, and future plans.

Aug 31, 2022 • 34min
Ep 5: Lucia Huang on Psychedelic Medicine and the Future of Mental Healthcare
Jacob sits down with Lucia Huang, co-founder and CEO of Osmind, to discuss new psychedelic and neuromodulation mental health treatments, how Osmind is furthering research around them, and what’s next for the space.

Aug 16, 2022 • 39min
Ep 4: Brad Smith on Improving Policy and Rural Healthcare
Jacob sits down with Brad Smith, founder of CareBridge, Main Street Health and Aspire and former head of CMMI, to discuss the novel ways he’s bringing risk-based models to rural healthcare and Medicaid and hear why he thinks CMMI programs haven’t worked to date.

14 snips
Aug 3, 2022 • 41min
Ep 3: Dr. Tom Lee on Amazon/One Medical, Galileo and Healthcare's Future
Dr. Tom Lee, founder of One Medical, Galileo and Epocrates discusses Amazon's acquisition of One Medical, the future of medical education, flaws in medical training, and consumer involvement in healthcare costs.

Jul 19, 2022 • 31min
Ep 2: Dr. Mandy Cohen on Medicaid Innovation and Succeeding Under Risk
Jacob sits down with Dr. Mandy Cohen - former Secretary of North Carolina’s Department of Health and Human Services, COO of the Center for Medicare & Medicaid Services and current CEO of Aledade’s newest business line Aledade Care Solutions. They discuss her work in North Carolina around Social Determinants of Health, how Medicaid policy and innovation works, the new business line she’s building at Aledade and what’s required for primary care practices to succeed under risk.

7 snips
Jul 5, 2022 • 29min
Ep 1: Adam Boehler on the Value Based Care Market and What's Next
Jacob sits down with Adam Boehler - former CEO of Landmark Health, Head of the Center for Medicare and Medicaid Innovation and current CEO of Rubicon Founders. They discuss how building a value-based care business has changed, how Adam came up with the idea for Landmark and his other businesses, what makes different patient segments a fit for value-based models and where the space is headed. They also touch on Adam's hopes for future policy and the changes he’s seen in healthcare talent.
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