Biohacking Beauty: The Anti-Aging Skincare Podcast

Marina Moiseyeva, a functional medicine practitioner and anti-aging nurse practitioner, discusses skin as a detox organ and how topicals and medications raise detox load. She covers sweating, lymphatic movement, GLP-1s and nutrient absorption, and why ‘‘Ozempic face’’ reflects muscle, bone, and nutrient loss rather than fat alone.

Advanced skin treatments often underperform for a reason rarely addressed: regeneration cannot occur in a chronically stressed or under-resourced system. Elevated cortisol, inflammation, and metabolic imbalance weaken collagen signaling and tissue repair before any device, injectable, or modality has a chance to work.In this episode of the Biohacking Beauty Podcast, we sit down with Joe Radich from R3 Health to unpack why physiological preparation determines treatment outcomes. We explore how internal factors like stress, hormones, micronutrients, and metabolic health shape skin regeneration, and why modalities like peptides, hyperbaric oxygen, and exosomes only work as well as the system they’re introduced into.Joe Radich is an NCCPA board-certified Physician Assistant specializing in regenerative medicine and the founder of R3 Health. He trains physicians and mid-level practitioners in stem cells, PRP, exosomes, and biohacking-based clinical protocols, with expertise spanning orthopedic, aesthetic, hair restoration, and regenerative applications.What's Discussed:(06:42) Why chronic stress and cortisol are silent drivers of visible skin aging(10:18) Preparing the body before skin treatments and why physiology determines outcomes(14:07) Why microneedling success depends on internal biology, not just technique(18:55) The most common lab patterns behind poor skin regeneration and chronic inflammation(24:31) Hormonal imbalance vs hormone deficiency and how both affect skin aging(33:41) GHK-Cu and peptides as signaling tools for connective tissue regeneration(38:09) Hyperbaric oxygen as a force multiplier for skin repair, recovery, and longevity(44:06) Exosomes and regenerative biologics and why sourcing and quality determine resultsFind more from Young Goose:VAMPIRE EXOSOMES → Professional Exosome Serum for Regeneration and Post-Treatment Recovery → Vampire ExosomesUse code PODCAST10 to get 10% off your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% off at www.younggoose.com    Instagram: @young_goose_skincareWinter Skincare Protocol: https://www.younggoose.com/pages/winter-protocol Find more from Joe Radich (R3 Health):Website: https://josephradich.com, https://r3health.coInstagram: @joeradich_

Skin sagging, crepiness, and loss of bounce are often blamed on collagen loss, yet the real driver sits elsewhere in the skin’s architecture. Elastin degradation accumulates quietly over time, shaping how skin functions long before changes fully register in the mirror.In this Biohacking Beauty episode, we unpack why rebuilding elastin is largely a myth, how elastin breakdown differs fundamentally from collagen loss, and how even a single period of stress can influence skin integrity for decades.We also examine how collagen is over-credited in conversations about sagging and how lasers and radiofrequency treatments can create temporary tightening while promoting long-term fibrotic remodeling that undermines true elasticity. Tune in.What's Discussed:(05:58) Why Elastin, Not Collagen, Drives Skin Bounce and Elastic Recovery(07:54) Elastin’s 70-Year Half-Life and Why Skin Aging Is Mostly About Preservation(11:39) Why Rebuilding Elastin Is Largely a Myth After Puberty(21:10) Why Collagen Loss Is Over-Credited in Skin Sagging(23:12) Lasers, RF and Fibrotic Remodeling vs True Skin Elasticity(26:50) The Elastin Enemies: UV, Oxidative Stress, Glycation and Inflammation(31:39) Preservation Over Correction: Building a Daily Elastin-Protective Strategy(34:01) Signal-Based Remodeling: Supporting Elastic Function Without Chronic InflammationFind more from Young Goose:VAMPIRE EXOSOMES: Professional Exosome Serum for Regeneration and Post-Treatment RecoveryUse code PODCAST10 to get 10% off your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% off at www.younggoose.com    Instagram: @young_goose_skincareFind our Winter Protocol here: https://www.younggoose.com/pages/winter-protocolFind our Elastin Action Protocol here: https://www.younggoose.com/pages/elastin-action-protocol-landing

Dylan Gemelli, a biohacking educator and podcast host, dives into the fascinating world of peptides and their impact on skincare. He reveals why oral peptides often fail and the impressive benefits of BPC-157 for gut healing and collagen repair. The discussion also covers the advantages of injectable peptides over traditional treatments, and how GHK-Cu peptides can rejuvenate skin and hair. Gemelli addresses the intriguing differences between neuromodulating peptides and Botox, and explains how PRP facials work through exosomes, paving the way for future innovations in skincare.

Winter transforms our skin, causing dryness and accelerating aging. Discover how lowered humidity and indoor heating affect moisture levels. The hosts highlight the importance of daily SPF, even with snow's UVA reflection. They dive into winter's hidden risks like glycation and recommend essential ingredients like ceramides and peptides for repair and hydration. Practical routines for different skin ages are laid out, emphasizing nutrition, sleep, and movement as keys to maintaining healthy skin during cold months.

Join Eva Hooft, a somatic and detox practitioner, as she unpacks the fascinating connection between unresolved emotions and skin health. Discover how stress patterns can trigger premature aging and why the liver plays a critical role in skin clarity. Eva introduces practical somatic practices for improving physical health, and discusses the impacts of mineral balance and heavy metals. Dive into the idea that skin is a reflection of inner safety and emotional regulation, revealing how addressing these elements can transform your skincare journey.

Everyone is chasing the next skincare hack, yet true beauty begins far deeper than a product. It grows through awareness, alignment, and how we move through life.In this episode, we sit down with beauty expert and coach Liz Kennedy to explore how biohacking, mindset, and consciousness work together to create what she calls magnetic beauty. We discuss how affirmations, community, and daily rituals strengthen your energy, as well as how outer practices such as peptides, NAD, and red light therapy enhance results when your inner world is balanced.Liz explains her approach to conscious biohacking and shares why practices like grounding, movement, and SPF are essential for long-term radiance. She also reveals how to integrate micro habits, her “pockets of peace” into modern routines while staying consistent, realistic, and connected.Liz Kennedy is a celebrity beauty expert, coach, and speaker who merges skincare science with consciousness and community. Through her events, workshops, and social media, she helps women cultivate beauty that reflects vitality, confidence, and purpose.We Also Discuss:(00:54) The Real Meaning of Magnetic Beauty and Conscious Biohacking(03:14) How Energy, Mindset, and Confidence Shape Physical Beauty(08:00) Daily Habits That Boost Radiance: Movement, SPF, and Grounding(12:20) Why Community and Female Connection Regulate Stress and Longevity(20:39) Aging with Power: Reframing How We See Time and Self-Love(31:14) Integrating Affirmations and Skincare for Emotional Resilience(34:13) The Truth About Peptides, NAD, and At-Home Biohacking(44:29) Cold Plunge Controversy: Why Some Methods May Disrupt Female BalanceFind more from Young Goose:Blue Peptide Spray: Cellular hydration meets antioxidant power Use code PODCAST10 to get 10% off your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% off at https://www.younggoose.com/    Instagram: @young_goose_skincareFind more from Liz Kennedy:Instagram: @ Liz Kennedy TikTok: lizkennedy__ Facebook: Liz Kennedy 

Many listeners asked us to go deeper into exosomes, and this episode expands on everything that most brands avoid talking about: count, consistency, purity, and microRNA composition. We explain why exosomes on a label don’t mean much without verified numbers, and how dose shapes whether the skin actually receives a biologically meaningful message.We walk through why platelet-derived exosomes offer the clearest communication to human skin, why microRNAs matter more than growth factors alone, and how publishing full sequencing data creates a new standard for transparency in longevity skincare. We also explore the synergy between exosomes and NAD+, how cellular energy drives repair, and why combining messenger and fuel creates a regenerative loop the skin can sustain.This episode gives listeners a clear, science-driven understanding of how exosome formulas should be evaluated and what truly defines high-performance regenerative skincare.As founders of Young Goose Skincare, we focus on bringing advanced longevity science into daily routines through transparency, validated potency, and clinically guided innovation.We Also Discuss:(00:19) Why “Exosomes on the Label” Tells You Almost Nothing(01:48) The Dose Problem: How Most Exosome Serums Miss Biological Activity(03:11) Why microRNA is the Real Engine Behind Skin Repair(05:16) The Transparency Gap in Skincare, and How We’re Closing It(09:21) Exosomes as Messages, NAD+ as the Battery(12:21) Clearing Senescent Cells and Restoring Youthful FunctionFind more from Young Goose:VAMPIRE EXOSOMES → Professional Exosome Serum for Regeneration and Post-Treatment Recovery → Vampire ExosomesUse code PODCAST10 to get 10% off your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% off at https://www.younggoose.com/    Instagram: @young_goose_skincare

Discover the fascinating world of exosomes as key players in skincare communication. Explore how these cellular messengers support skin repair and rejuvenation and how their effectiveness varies by type: plant, stem cell, and platelet-derived. Learn why aging disrupts cellular signals and how regenerative medicine has shifted the skincare landscape. Uncover the benefits of each exosome source and why platelet-derived ones are the gold standard. Plus, get insights on daily use and the importance of matching exosomal messages to skin biology for long-term benefits.

In this discussion, Olga from Natural Face Bible, a facial therapy educator known for introducing Japanese medical-grade face taping in North America, unpacks the real benefits of this practice. She explains how correct taping improves lymphatic flow, reduces stagnation, and softens dynamic wrinkles. With insights on anatomy and the importance of technique, Olga clarifies common misconceptions and highlights the synergy of face taping with massage and gua sha. She shares tips on application, safety, and how to integrate taping into a long-term skincare routine.