The Human Upgrade: Biohacking for Longevity & Performance
Dave Asprey
For more than a decade, Dave Asprey - the Father of Biohacking and creator of Bulletproof Coffee - has redefined what’s possible for the human mind and body. After more than a thousand episodes of Bulletproof Radio, he’s taking it to the next level with The Human Upgrade™ - a masterclass in biohacking, longevity, and performance optimization.Each episode explores cutting-edge science, advanced technology, and proven biohacks to help you upgrade your energy, focus, metabolism, and resilience. You’ll learn from world-class scientists, doctors, innovators, and thinkers leading breakthroughs in mitochondrial health, peptides, hormones, fasting, sleep, neuroplasticity, and more.This isn’t just self-improvement - it’s human enhancement backed by data.Every guest, every idea, every protocol you discover here moves you toward a longer, stronger, smarter life.Join The Human Upgrade™ with Dave Asprey - and learn how to live longer, think faster, and perform better.
Episodes
Mentioned books
Apr 21, 2020 • 1h
Covid-19 Turns Inflammation from Protective to Predatory – Dave Asprey with Dr. David Liepert : 690
Dr. David Liepert, a physician specializing in critical care and chronic pain, discusses the dual nature of inflammation, particularly in the context of COVID-19. He explains how inflammation shifts from protective to harmful, becoming a ‘cytokine storm.’ The conversation delves into innovative treatment options, like anti-inflammatory diets and the role of supplements. Liepert emphasizes the importance of understanding individual biochemistry and adapting health strategies for resilience, while also touching on the complex decision-making faced by medical professionals during a crisis.
Apr 17, 2020 • 56min
A Five-Step Formula to Make Money and a Difference – Lisa Sasevich : 689
Lisa Sasevich, an entrepreneur and author of "Meant for More," shares her inspiring journey from job loss to creating a $40 million home-based business. She emphasizes the power of recognizing one's unique value and reframing sales as a way to help others. Listeners learn about her five-step formula to generate income while making a difference, the importance of an entrepreneurial mindset, and transforming challenges into opportunities. Sasevich inspires everyone to embrace their potential and navigate financial growth ethically.
Apr 16, 2020 • 51min
Part 2-Ripple Effects of the Covid-19 Pandemic That We’re Ignoring: DNA Impacts with Mansoor Mohammed, Ph.D. : 688
In this engaging discussion, Mansoor Mohammed, Ph.D., a trailblazer in medical genomics and president of The DNA Company, dives into how genetics influences our responses to viral infections like COVID-19. He details specific genes, including SHMT1, that heighten inflammation and respiratory issues. Listeners learn about the importance of methylation and nutrient stacking for viral resilience. Innovative treatments such as lidocaine for inflammation management and new health tech developments emerge as pivotal topics, offering actionable insights to improve personal health.
Apr 14, 2020 • 48min
Part 1-Ripple Effects of the Covid-19 Pandemic That We’re Ignoring: DNA Impacts with Mansoor Mohammed, Ph.D : 687
Mansoor Mohammed, Ph.D., president of The DNA Company and a pioneer in medical genomics, discusses the hidden impacts of the Covid-19 pandemic. He reveals how genetics affect our ability to fight the virus and how stress, anxiety, and social isolation are creating a mental health crisis, especially among youth. The conversation also covers how lifestyle choices and genetic predisposition influence emotional resilience and the physical ramifications of the pandemic, emphasizing the urgent need for mental health support worldwide.
Apr 9, 2020 • 1h 16min
Overcoming Massive Adversity with Little Mind Hacks – Amy Purdy : 686
Amy Purdy, a Paralympic snowboarder, bestselling author, and motivational speaker, shares her incredible journey after losing both legs at 19. She dives into the mental resilience required to navigate her health crises, including a kidney transplant and recent health setbacks. Purdy discusses how she transformed adversity into empowerment, emphasizing the importance of focus and adaptability. She also reveals innovative techniques she's used to enhance health and recovery, inspiring listeners to embrace perseverance and creativity in the face of challenges.
Apr 8, 2020 • 52min
Parenting Through the New Norm: Tips for Connecting with Your Kids During Stressful Times – Dr. Stewart Friedman : 685
Dr. Stewart Friedman, an organizational psychologist and Wharton School professor, shares insightful strategies for parents navigating today's challenges. He emphasizes the importance of flexibility in work-life integration, urging parents to communicate openly with their kids. His book, "Parents Who Lead," offers leadership principles for effective parenting, encouraging involvement in household chores through purpose. Friedman's advice fosters resilience and personal growth while promoting a balance between self-care and family responsibilities. Humorously, they discuss virtual backgrounds, reflecting personal identity in remote work.
Apr 7, 2020 • 43min
How Virus Resistance Can Help You Live to 100 – Jamie Metzl : 684
In this discussion, guest Jamie Metzl, a leading futurist and geopolitical expert, shares insights on genetic engineering to enhance virus resistance. He highlights the balance of benefits and risks in modern genetics, exploring CRISPR technology's potential while questioning ethical implications. Metzl critiques the pandemic response and advocates for systemic health reforms, encouraging collective action and innovative governance. He also delves into biohacking for resilience, urging a unified approach to the evolving challenges facing humanity.
Apr 2, 2020 • 57min
Going Beyond the Human Mind to Discover Your Infinite Potential – Deepak Chopra : 683
Deepak Chopra, a pioneer in integrative medicine and personal transformation, dives deep into consciousness and the mind's potential. He challenges listeners to question reality and explore the concept of 'Metahuman'—the infinite essence beyond physical limitations. The discussion spans consciousness's role in health, how our perceptions influence aging, and the interplay between trauma and self-identity. Chopra also reflects on transcending fear of death and the transformative role of psychedelics, inviting a reimagining of existence.
7 snips
Mar 31, 2020 • 60min
Viruses: The Ultimate Gene Therapy Machines – Liz Parrish : 682
Liz Parrish, Founder and CEO of BioViva Sciences, is pioneering the use of gene therapy to extend healthy lifespans. She shares her experience as the first person to undergo dual gene therapies for aging and discusses how viruses can act as effective delivery systems for genes. The conversation dives into the ethical challenges of genetic engineering, the role of mitochondria in aging, and the potential of gene therapies to replace traditional medicine. With insights on enhancing athletic performance and the future of biohacking, it's a glimpse into the cutting edge of medical science.
Mar 27, 2020 • 1h 2min
How Harvard Researcher David Sinclair (and Dave Asprey) Manage COVID-19 Risk : 681
David Sinclair, a Harvard genetics professor and aging expert, shares insights on navigating health risks during the COVID-19 pandemic. He discusses effective lifestyle changes to boost immunity, such as diet and exercise, alongside the role of supplements like Vitamin D3 and zinc. The podcast dives into the rapid vaccine development process and the importance of balancing safety with efficacy. Sinclair also highlights the significance of home testing and personal health autonomy while emphasizing resilience and coping mechanisms in these challenging times.
