

The Human Upgrade: Biohacking for Longevity & Performance
Dave Asprey
For more than a decade, Dave Asprey - the Father of Biohacking and creator of Bulletproof Coffee - has redefined what’s possible for the human mind and body. After more than a thousand episodes of Bulletproof Radio, he’s taking it to the next level with The Human Upgrade™ - a masterclass in biohacking, longevity, and performance optimization.Each episode explores cutting-edge science, advanced technology, and proven biohacks to help you upgrade your energy, focus, metabolism, and resilience. You’ll learn from world-class scientists, doctors, innovators, and thinkers leading breakthroughs in mitochondrial health, peptides, hormones, fasting, sleep, neuroplasticity, and more.This isn’t just self-improvement - it’s human enhancement backed by data.Every guest, every idea, every protocol you discover here moves you toward a longer, stronger, smarter life.Join The Human Upgrade™ with Dave Asprey - and learn how to live longer, think faster, and perform better.
Episodes
Mentioned books

Oct 8, 2021 • 1h 28min
Mimetic Desire Shatters the Myth of Why You Want – Luke Burgis with Dave Asprey : 865
Luke Burgis, author of "Wanting: The Power of Mimetic Desire in Everyday Life," delves into the intriguing theory of mimetic desire, revealing how our wants are often shaped by imitation rather than authentic self-advocacy. He explores the societal pressures that drive our ambitions and the loneliness that can accompany success. The discussion also touches on the influence of charismatic leaders and the need for critical thinking amid information overload. Listeners are encouraged to reflect on their motivations and pursue desires that align with their true values.

5 snips
Oct 6, 2021 • 1h 32min
Relationship Goals: Your Gut Microbiome and Immune Function – Kiran Krishnan, Ph.D., with Dave Asprey : 864
Kiran Krishnan, Ph.D., a research microbiologist specializing in the human microbiome, shares insights on gut health's impact on immune function. He delves into the intricacies of the microbiome, explaining how inflammation drives gut damage and the necessity of dietary choices. Kiran introduces spore-forming probiotics and emphasizes their resilience, while exploring the gut-lung connection and its implications for overall health. Through practical advice and emerging science, he guides listeners on enhancing gut diversity for improved immune responses.

Oct 1, 2021 • 44min
How to Build Strength Faster – John Jaquish, Ph.D., with Dave Asprey, Part 2 : 863
John Jaquish, Ph.D., inventor of OsteoStrong and the X3 System, discusses revolutionary approaches to strength training and muscle gain. He emphasizes the benefits of elastic resistance over traditional weightlifting, significantly reducing injury risk. The conversation also dives into the impact of genetics on strength potential and debunks myths around testosterone therapy. Jaquish advocates for innovative fitness methods, linking exercise speed with optimal health outcomes and challenging societal beauty standards in fitness.

4 snips
Sep 29, 2021 • 40min
Building Strength Isn’t About Weight Lifting Anymore – John Jaquish, Ph.D., with Dave Asprey, Part 1 : 862
John Jaquish, Ph.D., an inventor and scientist known for his research on bone density, shares groundbreaking insights on muscle growth and bone health. He discusses the innovative bioDensity system that builds bone density and the X3 System, which allows for accelerated muscle gain without injury risks. Jaquish emphasizes the importance of bone density for long-term health and challenges traditional weightlifting methods. He also highlights the role of diet in metabolic health and introduces essential amino acids for muscle preservation.

Sep 24, 2021 • 13min
Mini-Episode: Cool Facts Friday #15
Discover the surprising effects of a ketogenic diet on brain cancer and the intriguing link between calf muscles and blood pressure. Find out how sunlight can enhance romantic passion and mental clarity. Learn about the benefits of time-restricted eating and an innovative method for transporting mouse sperm. This fun compilation of scientific insights will keep you informed about the latest advancements in health and wellness!

Sep 24, 2021 • 1h 23min
Hack Your Neurochemistry with Customized Nootropics – Mr. Noots & Matt Gallant : 861
Mark Allen Effinger, Chief Product Officer at Nootopia with a science and chemistry background, joins Matt Gallant, co-founder of BiOptimizers, known for innovating human performance. They dive into the fascinating world of nootropics, discussing the stark difference between their promises and realities. The duo highlights the uniqueness of individual brain chemistry and the importance of personalized nootropic stacks. They also share insights on how neurochemicals impact behavior and social interactions, with practical tips for maximizing nootropic benefits.

Sep 21, 2021 • 27min
Nutrition Goes Primal with Dr. Paul Saladino and Nora Gedgaudas : 860
Dr. Paul Saladino, a functional medicine practitioner, champions the carnivore diet and advocates for meat's central role in nutrition. Nora Gedgaudas, an expert in keto and ancestral diets, challenges conventional vegetarianism. They tackle the hidden dangers of plant toxins and omega-6 fats while sharing personal journeys from veganism. The discussion also dives into the significance of fatty acids and the integration of quantum biology in health improvement, ultimately promoting a diet focused on quality and primal living.

Sep 16, 2021 • 1h 11min
Kava: Psychedelic Benefits in an Alcohol Alternative – Cameron George with Dave Asprey : 859
Cameron George, founder of TRU KAVA and a researcher passionate about kava, discusses the many benefits of this South Pacific plant medicine. He reveals how kava serves as a natural alternative to alcohol, promoting relaxation and social connection without intoxication. The conversation covers kava's potential for anxiety relief and cognitive enhancement, likening its effects to microdosing psychedelics. George shares insights on kava’s cultural significance and its therapeutic potential for mental health, making a strong case for its growing popularity in the U.S.

Sep 14, 2021 • 51min
Ozone Therapy: Your New Favorite Biohack – Micah Lowe with Dave Asprey : 858
Micah Lowe, the 'Ozonaut' and expert in ozone therapy, shares his passion for harnessing ozone to improve health through enhanced oxygen intake and immune activation. He discusses how ozone therapy can boost athletic performance and cognitive function while reducing brain fog. Micah highlights different applications, from home-based therapy to its use in municipalities, and dispels myths surrounding ozone. He emphasizes the importance of medical-grade ozone equipment and its transformative potential as a health biohack for modern living.

Sep 9, 2021 • 50min
Speaker Preview 2: Human Upgrades at the 7th Annual Biohacking Conference : 857
Vishen Lakhiani, an author and consciousness engineer, discusses transforming outdated beliefs for personal growth. Panache Desai emphasizes the power of self-acceptance and insight in overcoming trauma, while Don Wood shares innovative approaches to trauma resolution through neuroscience. Dr. Ted Achacoso explores the intersection of AI and aging, revealing insights into anti-aging with NAD supplements. Together, they ignite conversations on self-awareness, resilience, and the metaphor of life as a video game, encouraging listeners to level up their lives.


