

The Human Upgrade: Biohacking for Longevity & Performance
Dave Asprey
For more than a decade, Dave Asprey - the Father of Biohacking and creator of Bulletproof Coffee - has redefined what’s possible for the human mind and body. After more than a thousand episodes of Bulletproof Radio, he’s taking it to the next level with The Human Upgrade™ - a masterclass in biohacking, longevity, and performance optimization.Each episode explores cutting-edge science, advanced technology, and proven biohacks to help you upgrade your energy, focus, metabolism, and resilience. You’ll learn from world-class scientists, doctors, innovators, and thinkers leading breakthroughs in mitochondrial health, peptides, hormones, fasting, sleep, neuroplasticity, and more.This isn’t just self-improvement - it’s human enhancement backed by data.Every guest, every idea, every protocol you discover here moves you toward a longer, stronger, smarter life.Join The Human Upgrade™ with Dave Asprey - and learn how to live longer, think faster, and perform better.
Episodes
Mentioned books

Feb 4, 2023 • 45min
Upgrade Spotlight: Connecting Ketones, Metabolism & Energy – H.V.M.N. : 1018
Latt Mansor, a metabolic biochemist leading research at H.V.M.N., dives into the fascinating world of ketones and their role in energy production. He explains how ketones differ from glucose and fat, offering superior efficiency and anti-inflammatory benefits. The conversation highlights the cognitive boost from ketone levels, enhancing decision-making and mental clarity. Mansor also discusses the latest developments in drinkable ketone supplements like Ketone IQ, emphasizing their positive effects on athletic performance, recovery, and overall metabolic health.

7 snips
Feb 3, 2023 • 1h 22min
How to Reclaim Feminine Divine Power – Kelly Brogan, M.D : 1017
Dr. Kelly Brogan, a holistic women's health psychiatrist, dives into reclaiming feminine power, often challenging conventional views. She discusses the dynamics of masculine and feminine energies, and the therapeutic aspects of BDSM in overcoming shame. The conversation touches on the importance of self-awareness in personal relationships, while exploring how societal expectations can hinder women's empowerment. Kelly also shares insights on self-kindness, vulnerability, and navigating the complexities of activism in a way that fosters personal growth.

Feb 1, 2023 • 59min
Biohacking for Women: How to Capture Your ‘Spark Factor’ – Molly Maloof, M.D. : 1016
Dr. Molly Maloof, a prominent physician and educator known for her expertise in women's biohacking, discusses her book "The Spark Factor." She emphasizes the importance of mitochondrial health and personalized wellness strategies tailored for women, particularly addressing energy levels and hormonal differences. Dr. Maloof shares insights on the impact of lifestyle choices, social connections, and the significance of nutrition on well-being. She also delves into the role of technology in health, encouraging listeners to embrace biohacking at their own pace.

12 snips
Jan 27, 2023 • 56min
Menopause: What to Know, What to Ask & What to Do – Mary Claire Haver, M.D. : 1015
Dr. Mary Claire Haver, a board-certified OB/GYN and menopause expert, shares her insights into managing menopause effectively. She discusses the importance of a holistic approach, covering nutrition, exercise, and stress management alongside Hormone Replacement Therapy. Dr. Haver highlights innovative ideas like banking ovarian tissue and sheds light on the Galveston Diet, focusing on its benefits for weight management. With a strong social media presence, she advocates for open conversations about women's health, aiming to empower women through education.

8 snips
Jan 25, 2023 • 1h 1min
How to Stack Cold Water, Sauna and Breathing to Accelerate Your Metabolism – Susanna Soeberg, Ph.D. : 1014
Susanna Soeberg, Ph.D., is a Danish researcher and expert in cold and heat therapy. In this discussion, she reveals how cold water immersion and sauna can supercharge your metabolism. Discover the science behind brown fat activation and the essential role of breathing techniques during cold exposure. Susanna emphasizes going all-in on cold for maximum benefits and shares her insights on balancing heat and cold for optimal health. Tune in for practical tips on winter swimming and how these practices can boost your well-being!

30 snips
Jan 20, 2023 • 1h 6min
How Quantum Energy Raises Your Biohacking to a New Level – Philipp Samor von Holtzendorff-Fehling : 1013
Philipp Samor von Holtzendorff-Fehling, a tech entrepreneur and founder of Leela Quantum Tech, dives into the fascinating world of quantum energy and its profound effects on our biology. He discusses groundbreaking studies that highlight how quantum frequencies enhance cellular function and overall health. Topics include improving blood health, neutralizing food allergies with energy tools, and the intriguing connections between consciousness and quantum mechanics. This lively conversation offers innovative insights into elevating personal biohacking and health optimization.

17 snips
Jan 18, 2023 • 55min
How Your Mitochondria Control Your Brain Energy – Chris Palmer, M.D. : 1012
Christopher Palmer, M.D., a Harvard psychiatrist and author of "Brain Energy," reveals groundbreaking insights about mental health. He discusses how mitochondrial dysfunction underlies various mental illnesses, challenging traditional views. Palmer dives into the benefits of the ketogenic diet for psychiatric health and emphasizes the importance of nutrition. He connects metabolic disorders with mental health issues, advocating for holistic treatment approaches. Personal stories and robust research underscore the urgency of addressing metabolic well-being for emotional resilience.

26 snips
Jan 13, 2023 • 1h 3min
Attention Span: How It’s Getting Lost & How to Get it Back – Gloria Mark, Ph.D. : 1011
In this fascinating discussion, Gloria Mark, a Chancellor’s Professor of Informatics at UC Irvine, dives into the alarming decline of attention spans in the digital age, now averaging just 47 seconds. She shares insights from her book, exploring how constant interruptions impact stress and productivity. Gloria outlines the four types of attention and offers practical strategies to regain focus and establish flow states. Listeners will also learn how to navigate decision fatigue and combat the anxiety spurred by constant digital engagement.

26 snips
Jan 10, 2023 • 1h 13min
Change Absolutely Everything With One Hack – Robert Waldinger, M.D. : 1010
Robert Waldinger, M.D., a Harvard psychiatrist and director of the influential Harvard Study of Adult Development, dives into the profound impact of relationships on our health and happiness. He reveals that social connections are vital, while loneliness can be detrimental. Waldinger discusses how to assess the quality of your relationships, introduces the concept of 'social fitness,' and highlights the surprising importance of work and casual relationships. He provides actionable insights on energizing connections and practicing generosity to enhance life satisfaction.

5 snips
Jan 7, 2023 • 32min
Upgrade Spotlight: How to Fight Zombie Cells and Win Aging – Neurohacker Collective : 1009
Greg Kelly, Director of Product Development at Neurohacker Collective, shares his expertise in nootropics and anti-aging. He reveals how senescent cells, or 'zombie cells,' hinder our aging process and explains how senolytics can help eliminate them. The discussion covers innovative approaches to enhance brain health and manage joint discomfort, highlighting new research on lifestyle changes and treatments. Kelly emphasizes the significance of removing these cells for improved well-being, proposing practical strategies for a healthier, more vibrant life.


