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Paul Saladino MD podcast

Latest episodes

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Feb 28, 2022 • 1h 17min

152. More myth debunking: TMAO, Neu5gc, Methionine/Glycine balance

Throughout my training and practice as a physician, I have come to one very disappointing conclusion:  Western medicine isn’t helping people lead better lives. Now that I’ve realized this, I’ve become obsessed with understanding what makes us healthy or ill. I want to live the best life I can and I want to be able to share this knowledge with others so that they can do the same. This podcast is the result of my relentless search to understand the roots of chronic disease. If you want to know how to live the most radical life possible I hope you’ll join me on this journey. 00:08:33 Podcast begins 00:09:35 What is epidemiology, why is it useful, and when can we use it? 00:12:40 Vegetables + Cardiovascular disease 00:19:40 Interventional studies on vegetables  00:27:22 What is TMAO (Trimethylamine N-oxide)? 00:32:30 Choline and Carnitine 00:37:40 Mainstream literature regarding TMAO 00:41:00 TMAO in fish 00:47:28 What is Neu5gc? 00:56:03 Methionine + Glycine balance, should we worry about excess Methionine from animal foods? Should we supplement with Glycine? 01:11:18 Evolutionary consistency + how much protein should we eat? Sponsors: Heart & Soil: www.heartandsoil.co  Shirttail Creek Farm: shirttailcreekfarm.com, use code CarnivoreMD $10 off order of $100 or more BluBlox: blublox.com, use code CarnivoreMD for 15% off White Oak Pastures: www.whiteoakpastures.com, use code CarnivoreMD for 10% off your first order Lets Get Checked: 20% off your order at www.TRYLGC.com/carnivoremd
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Feb 21, 2022 • 1h 22min

151. How plant defense chemicals may trigger autoimmunity. Is Nicotinamide Riboside BS? Is spirulina BS?

Throughout my training and practice as a physician, I have come to one very disappointing conclusion:  Western medicine isn’t helping people lead better lives. Now that I’ve realized this, I’ve become obsessed with understanding what makes us healthy or ill. I want to live the best life I can and I want to be able to share this knowledge with others so that they can do the same. This podcast is the result of my relentless search to understand the roots of chronic disease. If you want to know how to live the most radical life possible I hope you’ll join me on this journey. 00:10:57 Podcast begins 00:13:53 Paul’s framework and the hierarchy of the optimal human diet 00:19:00 Plant defense chemicals 00:19:44 Non-protein amino acids 00:34:14 Clip of Ben Patrick on The Joe Rogan Experience talking about plant defense chemicals 00:39:05 Joe Rogan clip ends 00:39:20 Hormetic properties of plant chemicals 00:43:33 Deep dive on non-protein amino acids 00:45:40 Link between plant toxins and multiple sclerosis 00:50:50 Link between non-protein amino acids and autoimmunity  1:00:00 Is algae BS? 1:04:08 Defense chemicals in seaweed 1:05:42 How to optimize cellular NAD levels 1:14:25 Why you do not need to take supplements (NR and NMN) Sponsors: Heart & Soil: www.heartandsoil.co  White Oak Pastures: www.whiteoakpastures.com, use code CarnivoreMD for 10% off your first order IceBarrel: www.icebarrel.com, use code PAUL for $125 off Lets Get Checked: 20% off your order at www.TRYLGC.com/carnivoremd Aura: 40% off your first order at www.aura.com/carnivore  
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Feb 14, 2022 • 1h 58min

150. Nick Bare interviews Paul on The Dangers of Seed oils

Nick Bare is an American YouTuber, Author, and entrepreneur. He is the CEO of Bare Performance Nutrition, founder of Embrace The Suck Training Program, and host of The Bare Performance podcast.     00:10:01 Podcast with Nick Bare begins 00:12:19 Hunting and consuming animal blood 00:19:20 Nutrition education and disease management versus biochemistry 00:20:53 Bow hunting and open fire cooking 00:23:53 The history and dangers of seed oils  00:34:53 Linoleic acids versus stearic acids, and saturated fats versus unsaturated fats 00:51:43 Where people are getting most of their linoleic acid, and thoughts on avocado/olive oil 00:57:53 Three main things to eliminate from your diet for improved health 1:02:53 Evolutionarily consistent foods and the sugar industry 1:06:38 Fruit as a primary carb source and Paul’s health journey  1:26:53 Obesity, appetite and weight loss 1:32:23 What is insulin resistance/metabolic dysfunction? 1:42:30 How do we recover from metabolic dysfunction and decrease linoleic acid intake? 1:48:53 Linoleic acid in formula versus breast milk 1:50:53 Avoiding seed oils while eating out     Where to find Nick Bare: Podcast: The Bare Performance Podcast Instagram: @thebareperformancepodcast Twitter: @BarePerformPod Website: www.bpnsupps.com
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Feb 7, 2022 • 1h 45min

149. How to fix mold toxicity with Evan Brand

Evan Brand, CFMP, FNTP. Energetic, dedicated, precise, and stubbornly addicted to helping people feel better through functional medicine and creatively crafted and scientifically proven protocols that he’s used to tackle his own health struggles and thousands of clients and practitioners around the world.   00:09:24 Interview with Evan Brand begins 00:11:05 Historical evidence for mold toxicity  00:17:04 Growing and storing grain as a source of mold 00:18:20 Where can humans get exposed to mold toxins? 00:30:00 Mold toxins in dog food 00:37:00 Detoxing mycotoxins + fertility 00:40:23 Synthetic fragrances 00:44:40 Effects of mycotoxins on the endocrine system 00:46:00 Paul’s thoughts on mold contamination in meat 00:52:10 Farming in Central America and soy deforesting the rainforest 00:58:20 Linoleic acid in eggs and breastmilk 1:00:22 Alpha-gal syndrome 1:04:20 Mold detection testing: Urine testing + ERMI home testing  1:13:00 Red yeast rice + statins 00:16:30 Mold injuries 1:18:30 Symptoms of mold toxicity 1:23:45 How can people begin to heal mold injuries 1:27:30 Binders to detox from mold 1:31:50 Candida  1:14:00 Breast implants + mold colonization 1:42:48 Coffee and chocolate are BS Listen to Paul Saladino on The Evan Brand Show: Dr. Paul Saladino - Are Vegetables Causing Your Symptoms? Dr. Paul Saladino MD on Carnivore Code  
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Feb 1, 2022 • 1h 20min

148. Are the Blue Zones BS or Not?

Throughout my training and practice as a physician I have come to one very disappointing conclusion: Western medicine isn’t helping people lead better lives. Now that I’ve realized this, I’ve become obsessed with understanding what makes us healthy or ill. I want to live the best life I can and I want to be able to share this knowledge with others so that they can do the same. This podcast is the result of my relentless search to understand the roots of chronic disease. If you want to know how to live the most radical life possible I hope you’ll join me on this journey. Time Stamps: 00:08:47 Podcast begins 0:9:30 Questioning plant based diets in blue zones 0:10:35 History of the blue zones 0:14:00 Clip of Dan Buettner, inventor of blue zones concept, in an interview with Mark Hyman 0:15:00 Regions of the world left out of the five “blue zones” 0:17:25 Debunking that plant based eaters have decreased mortality. Observational research versus Epidemiology. 0:35:31 Study highlighting that Asian people who increased meat intake have lower cardiovascular disease rates in men and breast cancer rates in women 0:40:46 Study highlighting correlation between red meat and male height 0:43:41 Examining blue zones in detail 1:06:50 Information about the 2022 Animal Based Gathering. (animalbasedgathering.com) 1:07:30 Study highlighting the unexpected effects of red meat in terms of longevity 1:15:00 Creating our own micro blue zones and the negative side effects of plant molecules Sponsors: Heart & Soil: www.heartandsoil.co  White Oak Pastures: www.Whiteoakpastures.com, use code: CarnivoreMD for 10% off your first order BluBlox: Blublox.com, use code CarnivoreMD for 15% your order Sacred Hunting: www.sacredhunting.com/Paul for $250 off your hunt Lets Get Checked: 20% off your order at www.TRYLGC.com/paul
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Jan 24, 2022 • 1h 36min

147. Ask Me Anything (AMA): Fructose, Fish Oil, Maple Syrup, and more…

Throughout my training and practice as a physician I have come to one very disappointing conclusion: Western medicine isn’t helping people lead better lives. Now that I’ve realized this, I’ve become obsessed with understanding what makes us healthy or ill. I want to live the best life I can and I want to be able to share this knowledge with others so that they can do the same. This podcast is the result of my relentless search to understand the roots of chronic disease. If you want to know how to live the most radical life possible I hope you’ll join me on this journey. 0:09:22:18 Podcast begins 0:11:31 Clip of Ben Patrick on Joe Rogan Podcast discussing animal based eating. 0:21:31 Paul’s commentary on Ben Patrick and Joe Rogan’s conversation. 0:22:01 Fructose fear mongering and thoughts on fruit in an animal based diet. 0:34:45 Connection between Nitric Oxide and insulin resistance. 0:40:23 Thoughts on maple syrup. 0:42:42 Why Paul originally introduced fruit and carbs into his diet.  0:45:35 Hierarchy of foods for humans that are hunter gatherers. 0:47:40 Commentary on Joe Rogan’s diet and thoughts on a chronic accumulation of plant defense chemicals from plant foods. 0:51:25 Reactive hypoglycemia and caffeine.  0:53:40 Omega 3 Fatty Acids: How valuable are they? Should we supplement with fish oil? 0:58:22 Fish oil is bullshit. 1:03:01 Paul shares his Essential and Metabolic Fatty Acid lab results from August 2021. 1:09:53 Nutrient adequacy on an animal based diet.  1:20:30 The Rotterdam study 1:27:00 Xenohormesis and the net negative of plant compounds. 1:30:15 Resveratrol versus fasting, heat and cold and mTOR. Sponsors: Heart & Soil: www.heartandsoil.co  White Oak Pastures: www.Whiteoakpastures.com, use code: CarnivoreMD for 10% off your first order BluBlox: Blublox.com, use code CarnivoreMD for 15% your order Sacred Hunting: www.sacredhunting.com/Paul for $250 off your hunt Lets Get Checked: 20% off your order at www.TRYLGC.com/paul Listen to Ben Patrick on Fundamental Health: How to make yourself a world-class athlete (or be free from knee pain forever!) with Knees Over Toes Guy, Ben Patrick  
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Jan 17, 2022 • 2h 16min

146. Does Red Meat Accelerate Aging, with David Sinclair PhD - UPDATE and REPOST

David Andrew Sinclair, PhD is an Australian biologist and professor of genetics. He is also a co-director of the Paul F. Glenn Center for Biology of Aging Research at Harvard Medical School, and is known for his research on aging with a focus on epigenetics. Time Stamps: 0:35:27 Podcast begins with David Sinclair 0:36:25 Is when we eat more important than what we eat? 0:38:45 What is the connection between time restrictive eating and longevity? 0:43:54 What causes us to age? 0:45:46 Epigenetic change. 0:52:03 What causes DNA breaks? 0:55:28 What plant foods create DNA breaks? 0:57:13 PARP enzymes  1:00:46 Where does NAD come from? How do we make it? What enzymes use it? 1:04:50 NAD recycling pathway. 1:12:13 Sirtuins. 1:24:14 What are the other longevity genes? (AMP kinase and mTOR) How are they connected to sirtuins? 1:31:50 Does being in a ketogenic state increase NAD? 1:40:30 Xenohormesis and plant molecules. 1:45:50 Resveratrol trials. 1:51:55 mTOR. 1:57:25 David’s thoughts on animal protein. 2:04:03 Meat consumption in relation to the environment and regenerative agriculture. 2:11:28 Where to find David Sinclair. David’s info: https://genetics.med.harvard.edu/sinc... https://lifespanbook.com/ Instagram: @davidsinclairphd Twitter: @davidasinclair Sponsors: Heart & Soil: www.heartandsoil.co White Oak Pastures: www.Whiteoakpastures.com, use code: CarnivoreMD for 10% off your first order The Cold Plunge: TheColdPlunge.com, use code CarnivoreMD for $111 off your cold plunge Eight Sleep: https://www.eightsleep.com/carnivoremd use code “CARNIVOREMD” to save $150 Sacred Hunting: www.sacredhunting.com/Paul for $250 off your hunt
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Jan 11, 2022 • 1h 18min

145. Heidi Montag (The Hills) Interviews Paul about Animal Based 30

Heidi Blair Pratt is an American television personality and singer. In 2006, she rose to prominence as one of the original cast members on The Hills, a former MTV reality television series. In 2007, Montag began working on her debut album, Superficial, which was released in January 2010. Montag and her husband Spencer Pratt, who was also featured on The Hills, have received much negative attention in the media, notably for their participation on the second season of I'm a Celebrity... Get Me out of Here!. In 2010, Montag gained further attention after having ten plastic surgery procedures done in a single day.   Time Stamps: 0:09:50 Podcast begins with Heidi Montag 0:12:20 Do I wear sunscreen in Costa Rica? What do I recommend for skin protection? 0:25:20 What about soaps and skin care products in general? Do I use toothpaste? 0:29:00 What do I recommend for makeup products for women? 0:34:20 How to make healthy eating a living for chldren easier and more socially accepted? 0:41:05 How bad is wine and adult indulgences? Can you get all your nutrients from meat, organs, and fruit? 0:49:50 Plants and defense mechanisms  0:58:05 How much fruit should someone eat per day? 1:02:20 Are there any supplements I recommend? 1:08:50 Is there a risk to eating raw foods? Is there a risk to taking Heart & Soil supplements? 1:10:05 What about chicken and pigs? 1:14:50 What about water? Does shower water matter?   Sponsors: Heart & Soil: www.heartandsoil.co  Animal-Based Gathering: https://www.animalbasedgathering.com/ Force of Nature Regenerative meats: Forceofnature.com use code CarnivoreMD22 for $15 off your entire order White Oak Pastures: www.Whiteoakpastures.com, use code: CarnivoreMD for 10% off your first order Lets Get Checked: 20% off your order at www.TRYLGC.com/paul
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Jan 4, 2022 • 44min

144. 2022 Kick Off Ask Me Anything (AMA): Cholesterol, Skin Care, Liver, and More

Throughout my training and practice as a physician I have come to one very disappointing conclusion:  Western medicine isn’t helping people lead better lives. Now that I’ve realized this, I’ve become obsessed with understanding what makes us healthy or ill. I want to live the best life I can and I want to be able to share this knowledge with others so that they can do the same. This podcast is the result of my relentless search to understand the roots of chronic disease. If you want to know how to live the most radical life possible I hope you’ll join me on this journey. Time stamps: 0:03:15 Podcast begins, my framework for everyone, should you listen to me? 0:09:00 What is the most ancestrally-consistent, nutrient-dense, and least offending diet for humans? 0:15:55 First question: What to reply to friends who say "I am killing myself" 0:20:00 Second question: What role does animal-based eating have on coronary artery disease? 0:24:15 Third question: What skin care products would you recommend for the face and eczema? 0:28:55 Doesn't the sun age us? 0:29:30 Fourth question: How can a child improve their gut microbiome? 0:31:15 Fifth question: What could be causing my muscle twitches? 0:33:30 Sixth question: Is the liver a filter for toxins? What are the benefits of eating liver?   Sponsors: Heart & Soil: www.heartandsoil.co  Force of Nature Regenerative meats: Forceofnature.com BluBlox: Blublox.com, use code CarnivoreMD for 15% your order Sacred Hunting: www.sacredhunting.com/Paul for $250 off your hunt White Oak Pastures: www.Whiteoakpastures.com, use code: CarnivoreMD for 10% off your first order
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Dec 28, 2021 • 1h 57min

143. The best of the Fundamental Health podcast, 2021 year in review

Throughout my training and practice as a physician I have come to one very disappointing conclusion: Western medicine isn’t helping people lead better lives. Now that I’ve realized this, I’ve become obsessed with understanding what makes us healthy or ill. I want to live the best life I can and I want to be able to share this knowledge with others so that they can do the same. This podcast is the result of my relentless search to understand the roots of chronic disease. If you want to know how to live the most radical life possible I hope you’ll join me on this journey.   Sponsors:   Heart & Soil: www.heartandsoil.co  White Oak Pastures: www.Whiteoakpastures.com, use code: CarnivoreMD for 10% off your first order BluBlox: Blublox.com, use code CarnivoreMD for 15% your order Sacred Hunting: www.sacredhunting.com/Paul for $250 off your hunt Lets Get Checked: 20% off your order at www.TRYLGC.com/paul

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