The Stem Cell Podcast

Dr. Sally Temple, scientific director of the Neural Stem Cell Institute, is a trailblazer in neural stem cell research. She discusses her groundbreaking discovery of a novel stem cell in the eye that holds promise for treating macular degeneration, the leading cause of blindness. The conversation also delves into the emotional impact of losing vision versus hearing and highlights the challenges gender disparity poses within the scientific community. Finally, they touch on innovative techniques in RPE cell research and preparations for future clinical trials.

Happy new year Stem Cell Podcast listeners, we are back to start off with an episode that looks backs at a year of science in 2013 and gives you our top 10 studies from both the stem cell world and science as a whole. We discuss a variety of topics from human cloning to going interstellar. It's been a great year for science despite threats to funding. Let's make sure science funding increases in 2014. Enjoy! Subscribe to our newsletter! Never miss updates about new episodes. Subscribe

Justine Miller, a PhD candidate from Lorenz Studer's lab at Memorial Sloan Kettering, discusses her groundbreaking research on aging neurons derived from stem cells. She reveals how they age in culture, shedding light on neurodegeneration and the challenges in modeling such diseases. The conversation touches on innovative gene editing techniques like CRISPR and the implications of recent findings on male birth control. Join them as they explore the intersection of neuroscience, aging, and cutting-edge research methodologies.

Get ready for a holiday science treat! Dive into fascinating topics like the biology behind our fear of snakes, the connection between genes and Alzheimer's, and shocking findings from the mummified past. Discover groundbreaking advancements in stem cell research, including potential treatments for ALS. Plus, hear about the cosmic wonders like gamma-ray bursts and the rising threat of resistant bacteria in hospitals. It's a mix of light-hearted banter and serious science that’s sure to intrigue!

Dr. Asif Maroof, a post-doctoral fellow at the Harvard Stem Cell Institute specializing in ALS, delves into groundbreaking research on the C9orf72 gene linked to the neurodegenerative disease. He shares insights on how this gene affects motor neuron health and disease progression, shedding light on ALS's complexities. The discussion also touches on the importance of community engagement in scientific research, and the potential of cell-based therapies in treating neurological conditions. Expect fascinating nuggets about genetics and global health along the way!

Delve into the complexities of Parkinson's disease, including its historical context and the vital role of dopamine neurons. Discover the promising potential of stem cell therapy, including advanced techniques in neuron generation and the ethics surrounding fetal tissue. The discussion also sheds light on recent innovations, from deep brain stimulation to the significant impact of the microbiome on neurological health. Plus, enjoy some light-hearted lab anecdotes about the trials of pipette usage!

Dr. Carl P. Wonders, the scientific affairs manager for the ISSCR, joins to discuss the highlights of the upcoming ISSCR meeting and the society's roles in promoting stem cell research. They dive into the transformative advances in creating 3D pancreas models for diabetes management and celebrate research milestones while addressing challenges like fraudulent publications. Hilarity ensues as the scientists share humorous anecdotes from their lab experiences, making for an engaging and informative conversation about the future of stem cell therapies.

Dr. Daylon James, an expert in cardiovascular and hematopoietic cells, takes listeners on a fascinating journey through the world of blood stem cells. He discusses innovative strategies for deriving blood components from stem cells and their potential in treating diseases like cancer. The conversation delves into the evolution of methodologies in stem cell research, addressing both challenges and breakthroughs. Additionally, the episode covers significant issues like CTE in the NFL and the impact of diversity in scientific research, making for a well-rounded exploration of current scientific topics.

Dr. Jacob Hanna, a distinguished scientist at the Weizmann Institute of Science, reveals his team's groundbreaking 100% efficiency in reprogramming somatic cells to pluripotent cells. The conversation dives into the delicate nature of embryonic stem cells and the critical role of mitochondrial functions in cellular processes. Additionally, the impact of the U.S. government funding crisis on scientific research is discussed, alongside innovative advancements such as CRISPR and the enhancement of reprogramming techniques. It's a deep dive into the future of stem cell science!

Dr. Juergen Knoblich, a scientist at the Institute of Molecular Biotechnology in Vienna and senior author on a groundbreaking Nature paper, discusses innovative approaches in stem cell research. He elaborates on in vivo reprogramming techniques that transform somatic cells into induced pluripotent stem cells. Additionally, Knoblich shares insights into the creation of mini cerebral cortices from human embryonic stem cells, exploring their implications for understanding brain development and potential therapies.