Dr. Dieter Egli, a senior research fellow at the New York Stem Cell Foundation, dives into the fascinating world of somatic cell nuclear transfer (SCNT) and its application in generating embryonic stem cell lines. He shares insights from his groundbreaking research on creating therapeutic cells for diabetes. The conversation also navigates the ethical challenges of egg donation for research and public perceptions surrounding SCNT. Egli's journey highlights both the promising advancements and the complexities inherent in the evolving landscape of stem cell science.
Dr. Dieter Egli's work on somatic cell nuclear transfer (SCNT) is paving the way for personalized embryonic stem cell lines for disease treatment.
The Stem Cell Podcast is enhancing audience engagement by encouraging listeners to share their experiences and opinions on stem cell research at upcoming events.
Challenges in the U.S. biomedical research system highlight the need for reforms in funding and job security for emerging researchers.
Deep dives
Milestone of Episode 20
The hosts reflect on the significance of reaching their twentieth episode in the Stem Cell Podcast series. They express gratitude for the audience's engagement and the growing interest in stem cell research within the public domain. The conversation highlights how listener feedback inspires the production team to create even better content, emphasizing the importance of community interaction. Excitement builds around upcoming events, particularly the ISSCR meeting in Vancouver, which promises to provide further opportunities for engagement with their audience.
Audience Involvement Initiative
The hosts introduce an initiative to foster greater audience participation by encouraging listeners to share their experiences and rants related to stem cell research. They plan to set up a booth at the ISSCR to record these stories, inviting attendees to voice their opinions and experiences on the podcast. The initiative is geared towards enhancing the show's connection with its listeners, with the most compelling rants being featured in future episodes. This approach aims to create a more interactive and responsive podcasting environment.
Upcoming Guest and Expert Insights
The episode previews an upcoming guest, Dr. Dieter Egli, a senior research fellow at the New York Stem Cell Foundation, who specializes in somatic cell nuclear transfer (SCNT). The hosts note the growing recognition of SCNT in scientific discussions and its relevance to stem cell research, particularly concerning disease-specific stem cell lines. Elaboration on Dr. Egli's research reveals a focus on developing embryonic stem cell lines from diabetic patients, marking significant progress in addressing medical conditions through stem cell therapy. This highlights the podcast's commitment to both educational content and the dissemination of cutting-edge scientific advancements.
Recent Scientific Developments
In this segment, the hosts review recent studies and findings in the realm of biomedical research, ranging from fruit fly studies to the implications of green tea on pancreatic cancer. They discuss advancements in understanding immune responses and the potential of innovative therapies for various diseases. The dialogue encapsulates the excitement and unpredictability of scientific discovery, with implications for future treatments and biomedical applications. This segment serves to underscore the importance of staying informed about ongoing research within the community of stem cell science.
Opinion on Biomedical Research Funding Challenges
A discussion ensues regarding the sustainability of the biomedical research system in the U.S., highlighting the imbalance between the increasing number of trainees and the limited funding opportunities. The hosts share insights from an opinion piece suggesting potential reforms, including requiring graduate students to secure their own funding. This conversation emphasizes the challenges faced by new researchers in securing jobs and funding, alongside the pressures of hyper-competition in academia. The overall tone reflects a critical examination of the current state of research funding and its long-term implications for the scientific community.
Guest:
Dr. Dieter Egli from the New York Stem Cell Foundation joins the hosts to talk about his work in using SCNT to derive new embryonic stem cell lines. They discuss his previous and current work, including his latest story published in Nature.
Resources and Links
Sensing of Amino Acids in a Dopaminergic Circuitry Promotes Rejection of an Incomplete Diet in Drosophila
Histone Modifications Are Associated with Delta(9)-Tetrahydrocannabinol-Mediated Alterations in Antigen-Specific T Cell Responses
Compound in Saliva Helps Protect Our Cells from Toxins in Coffee, Tea, Study Shows
A Molecular Basis for Classic Blond Hair Color in Europeans
Engineering a Memory with LTD and LTP
Green Tea Component Upsets Cancer Cell Metabolism
Photoactivation of Endogenous Latent Transforming Growth Factor–β1 Directs Dental Stem Cell Differentiation for Regeneration
Targeting CXCL12 From FAP-Expressing Carcinoma-Associated Fibroblasts Synergizes with Anti–PD-L1 Immunotherapy in Pancreatic Cancer
Fighting Back: Patient's Own Immune Cells Tackle Cervical Cancer
A Draft Map of the Human Proteome
Abnormal Neuronal Differentiation and Mitochondrial Dysfunction in Hair Follicle-Derived Induced Pluripotent Stem Cells of Schizophrenia Patients
Role of the Primate Ventral Tegmental Area in Reinforcement and Motivation
Tai Chi Intervention Increases Progenitor CD34+ Cells in Young Adults
Unconditional Quantum Teleportation between Distant Solid-State Quantum Bits
Remission of Disseminated Cancer after Systemic Oncolytic Virotherapy
Less Pain (Receptors) Means a Longer Life
Mice with Mohawks Reveal Two Biological Pathways Linked with Autism Behaviors
CC Sabathia Ready to Throw for First Time since Stem-Cell Treatment for Knee
New Record Highs In Moral Acceptability - Premarital Sex, Embryonic Stem Cell Research, Euthanasia Growing in Acceptance
The Broad Foundation Advances Stem Cell Research at USC
Obokata Agrees to STAP Experiment
Inside a Corrupt Stem Cell Research Lab
EU Commission Rejects Petition to Stop Funding Embryonic Stem Cell Research
Blonde Is Just a Matter of a Tiny Stem Cell Molecule Tweak, Says New Research
Modulating Innate Immunity Improves Hepatitis C Virus Infection and Replication in Stem Cell-Derived Hepatocytes
The Age and Genomic Integrity of Neurons after Cortical Stroke in Humans
Photo Reference: Courtesy of Dr. Dieter Egli
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